Fmoc-Asn(Trt)-OH
|
|
Fmoc-Asn(Trt)-OH 속성
- 녹는점
- 201-204 °C(lit.)
- 알파
- -16 º (c=1, MeOH)
- 끓는 점
- 858.1±65.0 °C(Predicted)
- 밀도
- 1.271±0.06 g/cm3(Predicted)
- 굴절률
- -19 ° (C=1, DMF)
- 저장 조건
- 2-8°C
- 용해도
- <0.00005g/l
- 산도 계수 (pKa)
- 3.79±0.10(Predicted)
- 물리적 상태
- powder to crystal
- 색상
- 흰색에서 거의 흰색
- optical activity
- [α]20/D 15.0±1°, c = 1% in methanol
- BRN
- 4343823
- InChIKey
- KJYAFJQCGPUXJY-UUWRZZSWSA-N
- SMILES
- C(O)(=O)[C@H](CC(N)=O)N(C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O)C(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1
- CAS 데이터베이스
- 132388-59-1(CAS DataBase Reference)
Fmoc-Asn(Trt)-OH C화학적 특성, 용도, 생산
개요
Fmoc-Asn(Trt)-OH prevents the possibility of the amide side chain from undergoing dehydration side reactions during activation, especially with carbodiimide reagents. Fmoc-Asn(Trt)-OH dissolves readily in all standard peptide synthesis reagents, while Fmoc-Asn-OH is only somewhat soluble in NMP or DMF. The trityl group is removed with TFA. This reaction is usually complete within 1 hour at room temperature, but is slower when the Asn(Trt) residue in at the N-terminal of the peptide. In these cases, the deprotection reaction should be extended to 2 hours.화학적 성질
white crystal powde용도
Fmoc-Asn(Trt)-OH, is an amino acid derivative used in chemical synthesis and peptide chemistry.제조 방법
Synthesis of Fmoc-Asn(Trt)-OH:Step 1: Crystallization to form N'-Trityl-L-asparagine crystals.
Step 2: Centrifugation to extract N'-Trityl-L-asparagine crystals.
Step 3: Washing to remove residual starting materials in the synthesis.
Step 4: Extraction to obtain N-Acetyl-L-asparagine.
Step 5: Centrifugation to extract N'-Trityl-L-asparagine.
Step 6: Drying to obtain the final product.
This synthesis method effectively removes residual synthetic materials such as trifluoroacetic acid, maleic anhydride, and epichlorohydrin, which are similar in chemical properties to N-Acetyl-L-asparagine, from the product during the production process. The purification method is simple and the product obtained has high purity.
Fmoc-Asn(Trt)-OH 준비 용품 및 원자재
원자재
준비 용품
Fmoc-Asn(Trt)-OH 공급 업체
글로벌( 437)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Lanxi Xingnuo Import and Export Trading Co., Ltd | +86-15888978871 +86-13901546477 |
sales@xingnuotraders.com | China | 163 | 58 |
Wuhan senwayer century chemical Co.,Ltd | +undefined-27-86652399 +undefined13627115097 |
market02@senwayer.com | China | 903 | 58 |
Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 |
sales@ichemie.com | China | 990 | 58 |
Chengdu Baishixing Science and Technology Industry Co.,Ltd | +86-15008457246 +86-15008457246 |
yuki@cd-bsx.com | China | 53 | 58 |
Sichuan HongRi Pharma-Tech Co.,Ltd | +86-028-64841719 +8617390183901 |
daisy@enlaibio.com | China | 1106 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 18628 | 58 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32836 | 60 |
AB PharmaTech,LLC | 323-480-4688 |
United States | 989 | 55 |
Fmoc-Asn(Trt)-OH 관련 검색:
메톡시카보닐술페닐클로라이드 P-톨루엔설폰 산 9-플루오레닐메틸 클로로폼산 알파-메틸 스타이렌 L-베타-아스파라긴 트리틸클로라이드 카보닐 황화합물 1-[[(9H-플로렌-9-일메톡시)카보닐]옥시]-2,5-필롤리딘디온 톨루엔 니켈카르보닐
Trityl candesartan
Fmoc-Asp(OtBu)-OH
Trityl Irbesartan
Trityl candesartan cilexetil
Nalpha-Fmoc-Ndelta-trityl-L-glutamine
D-(-)-Asparagine monohydrate
L-Fmoc-Aspartic acid alpha-tert-butyl ester
Fmoc-Lys(Boc)-OH