인슐린
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인슐린 속성
- 녹는점
- 233 °C
- 밀도
- 1.09 g/cm3
- 저장 조건
- 2-8°C
- 용해도
- 산성화된 물, pH 2.0: 2 mg/mL
- 물리적 상태
- 액체
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
안전지침서 | 22-24/25 | ||
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WGK 독일 | 3 | ||
RTECS 번호 | NM8900250 | ||
F 고인화성물질 | 3-10 | ||
유해 물질 데이터 | 9004-10-8(Hazardous Substances Data) |
그림문자(GHS): |
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신호 어: | Danger | ||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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인슐린 C화학적 특성, 용도, 생산
개요
Insulin is a polypeptide hormone that consists of two peptide chains bonded by two disulfide bonds. The two chains are designated A and B. The A chain consists of 21 amino acids with a third internal disulfidebond, and the B chain contains the remaining 30 amino acids. All vertebrates produce insulin and the structure is similar in these species. For example, the insulin produced in humans and porcine species differs by only one amino acid, and humans and bovine insulin differ by three amino acids. Insulin plays a crucial role in several physiological processes. These include the regulation of sugar in the body, fatty acid synthesis, formation of triglycerides, and amino acid synthesis.Insulin also promotes the storage of glucose as glycogen in the liver. In this manner, insulin maintains glucose at a stable level in the bloodstream. Insulin is most closely associated with diabetes. Diabetes results in excess blood glucose levels (hyperglycemia) and the inability of cells to absorb glucose, which in turn deprives them of energy.
역사
Insulin derives its name from the Latin word insula for island. Insulin is produced in the pancreas by β-cells in the islets of Langerhans (α-cells in the pancreas produce glucagon). Paul Langerhans (1847–1888) discovered the islets of Langerhans, which were subsequently shown to secrete insulin. Insulin binds to insulin receptors on cells and produces biochemical changes that allow the cells to take in glucose.Diabetes has been prevalent in humans throughout history, but relief from the disease was not available until the 20th century.The termdiabetes comes from the Greek words diabainein, meaning to pass through or siphon.In the late 1800s,it was known that diabetes was related to the pancreas,but it was not known exactly how. In 1901, Eugene Opie (1873–1971) determined that diabetes was related to the islets of Langerhans. During the early 20th century, knowledge was advanced on ductless glands and endocrine secretions that fed directly into the bloodstream.Diseases were treated with extracts obtained from glands.
용도
Insulin plays a crucial role in several physiologicalprocesses. These include the regulation of sugar in the body, fatty acid synthesis, formation oftriglycerides, and amino acid synthesis.=Insulin also promotes the storage of glucose as glycogenin the liver. In this manner, insulin maintains glucose at a stable level in the bloodstream.Insulin is most closely associated with diabetes.Diabetes must be managed by monitoring blood sugarlevels throughout the day, and using this information to adjust the diet and activities to keepblood glucose in an acceptable range; Insulin is usually administered through injections, but it can be deliveredusing other methods. Insulin pumps are small electronic devices that deliver insulin accordingto a programmed schedule throughout the day. In recent years oral sprays have beendeveloped to augment but not replace injected insulin. Another area of interest is deliveryusing dermal patches. Insulin cannot be delivered using conventional pills because stomachacidity denatures insulin. Although lack of insulin results in hyperglycemia,it is importantwhen administering insulin to prevent hypoglycemia. In hypoglycemia blood sugar is too low.Hypoglycemia in diabetics can occur from too much insulin, lack of food, exercise, or lackof carbohydrates. Its symptoms include increased heart rate, nervousness, perspiration, andshakiness. When this condition is recognized, diabetics consume carbohydrates such as candy,fruit,or fruit juice to boost blood sugar levels. In extreme cases,a person can have a severereaction and experience seizures or fall into a coma. Severe reaction to insulin is referred toas insulin shock.
정의
ChEBI: A peptide hormone produced in the pancreas and involved in regulating the metabolism of carbohydrates (particularly glucose) and fats. Commonly thought of as a protein, it consists of two petide chains, one containing 21 amino acid residues and the other c ntaining 30; the chains are joined together by 2 disulfide bonds. Recombinant insulin is identical to human insulin, but is synthesised by inserting the human insulin gene into E. coli, which then produces insulin for human use. It is used in he treatment of type I and type II diabetes.인슐린 준비 용품 및 원자재
원자재
INSULIN
DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS*
Α-protein
zinc compound amino acid complex
INSULIN
저마늄(게르마늄)
Beef Pancreas Glands
에틸알코올
준비 용품
인슐린 공급 업체
글로벌( 38)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
ARCTIC EXPORTS INC | +1-3026880818 +1-3026880818 |
ARCTICEXPORTSINC@GMAIL.COM | Canada | 69 | 58 |
CONTIDE BIOTECH CO.,LTD | +852-53358525 |
xena@healthtide-api.com | China | 568 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21668 | 55 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 |
sales@tnjchem.com | China | 34571 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 |
1026@dideu.com | China | 8853 | 58 |
AFINE CHEMICALS LIMITED | +86-0571-85134551 |
info@afinechem.com | China | 15395 | 58 |
Apeloa production Co.,Limited | +8619933239880 |
admin@apcl.com.cn | China | 853 | 58 |
Wuhan kemike Biomedical Technology Co., Ltd | 13163388153 13163388153 |
yeqiu416@163.com | China | 9952 | 58 |
BOC Sciences | 1-631-485-4226; 16314854226 |
info@bocsci.com | United States | 14059 | 65 |
GIHI CHEMICALS CO.,LTD | 0086-571-86217390 |
Sales@gihichem.com | China | 861 | 58 |
인슐린 관련 검색:
아세틸아세토산 제2철 코발트(II) 아세틸아세토네이트 하이드레이트 디스프로슘 트리(2,2,6,6-테트라메틸-3,5-헵탄디오네이트) 알루미늄 아세틸아세토네이트 실버 아세틸아세토네이트 아세틸아세톤산 구리 장미 벵갈 나트륨 이노시톨
1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
Tosylmethyl isocyanide
DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
SALCOMINE
Benzyl isocyanide
N-BUTYLISOCYANIDE
Ethyl isocyanoacetate
METHYL ISOCYANOACETATE
Tris(2,4-pentanedionato)chroMiuM(III)
TERT-BUTYL ISOCYANIDE