Obtustatin

Obtustatin 구조식 이미지
카스 번호:
상품명:
Obtustatin
동의어(영문):
Obtustatin;CTTGPCCRQCKLKPAGTTCWKTSLTSHYCTGKSCDCPLYPG(MODIFICATIONS: DISULFIDE BRIDGE: 1-10,6-29,7-34,19-36)
CBNumber:
CB43367986
분자식:
포뮬러 무게:
0
MOL 파일:
Mol file

Obtustatin 속성

물리적 상태
Solid
색상
White to off-white

안전

Obtustatin C화학적 특성, 용도, 생산

효소 저해제

This 41-residue disintegrin (FW = 4401 g/mol; Sequence CTTGPCCRQ CKLKPAGTTCWKTSLTSHYCTGKSCDCPLYPG, with disulfide bonds at Cys1-Cys10, Cys6-Cys29, Cys7-Cys34, and Cys19-Cys36) from the venom of the blunt-nosed viper Vipera lebetina obtusa exhibits tight binding to integrins, inhibiting platelet aggregation, IC50 = 2 nM. It is the shortest polypeptide to contain an integrin-recognition loop. Target(s): Obtustatin is a highly potent integrin α1β1 inhibitor (IC50 = 0.8 nM for α1β1 binding to type IV collagen), displaying specificity for α1β1 over α2β1, αIIbβ3, αvβ3, α4β1, α5β6, α9β1 and α4β7.

Obtustatin 준비 용품 및 원자재

원자재

준비 용품


Obtustatin 공급 업체

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