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1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL

1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL 구조식 이미지

카스 번호:: 253449-04-6

상품명:: 1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL

동의어(영문):: WISKOSTATIN;Wiskostatin - CAS 253449-04-6 - Calbiochem;1-(3,6-dibromocarbazol-9-yl)-3-(dimethylamino)propan-2-ol;3,6-Dibromo-α-[(dimethylamino)methyl]-9H-cabazole-9-ethanol;3,6-Dibromo-α-[(dimethylamino)methyl]-9H-carbazole-9-ethanol;1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL;9H-Carbazole-9-ethanol, 3,6-dibromo-α-[(dimethylamino)methyl]-;1-(3,6-Dibromo-9H-carbazol-9-yl)-3-(dimethylamino)propan-2-ol 97%;9H-Carbazole-9-ethanol, 3,6-dibroMo-alpha-[(diMethylaMino)Methyl]-;3,6-Dibromo-9-[3-(dimethylamino)-2-hydroxyprop-1-yl]-9H-carbazole, 3-(3,6-Dibromo-9H-carbazol-9-yl)-N,N-dimethyl-2-hydroxypropylamine

CBNumber:: CB4347723

분자식:: C17H18Br2N2O

포뮬러 무게:: 426.15

MOL 파일:: 253449-04-6.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 87

1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL 속성

녹는점: 153-155

끓는 점: 320.2±22.0 °C(Predicted)

밀도: 1.62±0.1 g/cm3(Predicted)

저장 조건: 2-8°C

용해도: DMSO: 용해성10mg/mL, 투명

산도 계수 (pKa): 14.40±0.20(Predicted)

물리적 상태: 흰색 고체

색상: 흰색에서 베이지색

안정성: 제공된 대로 구매일로부터 2년 동안 안정적입니다. DMSO 또는 에탄올 용액은 -20°에서 최대 3개월 동안 보관할 수 있습니다.

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

위험품 표기	Xi,T
위험 카페고리 넘버	25
안전지침서	45
유엔번호(UN No.)	UN 2811 6.1 / PGIII
WGK 독일	3
위험 참고 사항	Irritant
위험 등급	6.1
HS 번호	2933998090

그림문자(GHS):

신호 어:

Danger

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H301	삼키면 유독함	급성 독성 물질 - 경구	구분 3	위험		P264, P270, P301+P310, P321, P330,P405, P501
H413	장기적 영향에 의해 수생생물에 유해의 우려가 있음	수생 환경유해성 물질 - 만성	구분 4

예방조치문구:

P264	취급 후에는 손을 철저히 씻으시오.
P264	취급 후에는 손을 철저히 씻으시오.
P270	이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.
P273	환경으로 배출하지 마시오.
P301+P310	삼켰다면 즉시 의료기관(의사)의 진찰을 받으시오.
P405	밀봉하여 저장하시오.
P501	...에 내용물 / 용기를 폐기 하시오.

NFPA 704

	0
2		0

1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL C화학적 특성, 용도, 생산

용도

Wiskostatin has been used:

as a small-molecule inhibitor of Wiskott-Aldrich syndrome protein (WASP) in human osteosarcoma U2OS cells and mouse-tail fibroblast cell lines
as a neural (N)-WASP inhibitor in cultured neurons and in the human embryonic kidney (HEK293) cells expressing HA-Parkin
as a neural (N)-WASP inhibitor in dorsal root ganglion (DRG) cells to investigate vascular endothelial growth factor (VEGF) effect on the actin related protein 2/3 complex (Arp 2/3)

일반 설명

Wiskostatin is a dibrominated carbazole. The N-alkylated side chain has a chiral hydroxyl group and a terminal tertiary amine.

Biochem/physiol Actions

Wiskostatin is a selective inhibitor of N-WASP, a ubiquitously expressed member of the Wiskott-Aldrich Syndrome protein (WASp) family that regulates actin polymerization. Wiskostatin inhibits actin-dependent cellular functions, including migration, transmembrane transport and phagocytosis.

1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL 준비 용품 및 원자재

원자재

준비 용품

1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL 공급 업체

글로벌( 87)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
Aceschem Inc.	+1-817863-6948 +1-（817）863-6948	sales@aceschem.com	United States	19632	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Nanjing Chemlin Chemical Co., Ltd	025-83697070	info@chemlin.com.cn	China	19172	64
Thermo Fisher Scientific	800-810-5118	cnchemical@thermofisher.com	China	17770	75
9ding chemical ( Shanghai) Limited	4009209199	sales@9dingchem.com	China	22514	55
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51456	80
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
Target molecule Corp.	857-239-0968	service1@targetmol.com	United States	2559	60

1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL 관련 검색:

BKM120 (NVP-BKM120, Buparlisib) S-Trityl-L-cysteine ANSAMITOCIN P-3 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide SALOR-INT L144428-1EA 1-(3,6-DIBROMO-CARBAZOL-9-YL)-3-PYRROLIDIN-1-YL-PROPAN-2-OL 1-(3,6-DIBROMO-CARBAZOL-9-YL)-3-[4-(4-FLUORO-PHENYL)-PIPERAZIN-1-YL]-PROPAN-2-OL SALOR-INT L150053-1EA (+)-1-(3,6-DIBROMOCARBAZOL-9-YL)-3-PIPERAZIN-1-YL-PROPAN-2-OL, BIS TFA 3,6-DIBROMO-ALPHA-(1-PIPERAZINYLMETHYL)-9H-CARBAZOLE-9-ETHANOL DIHYDROCHLORIDE 1-(4-[2-HYDROXY-3-(1,3,6-TRIBROMO-9H-CARBAZOL-9-YL)PROPYL]PIPERAZINO)-3-(1,3,6-TRIBROMO-9H-CARBAZOL-9-YL)PROPAN-2-OL DIHYDROCHLORIDE 1-(3,6-DIBROMO-9H-CARBAZOL-9-YL)-3-(DIMETHYLAMINO)PROPAN-2-OL