에틸-(2-페닐술포메틸)-아크릴레이트

에틸-(2-페닐술포메틸)-아크릴레이트 C화학적 특성, 용도, 생산

용도

Ethyl 2-((phenylsulfonyl)methyl)acrylate can be used in the synthesis of ethyl 2-{[(1s,2r,3r,5s)-2,6,6-trimethylbicyclo[3.1.1]hept-3-yl]methyl}acrylate that it is radical allylation of b-alkylcatecholboranes.

Synthesis

Ethyl 2-((phenylsulfonyl)methyl)acrylate is synthesized from ethyl 2-(bromomethyl)acrylate.

Step: To a solution of ethyl 2-(bromomethyl)acrylate (1.99 g, 10.4 mmol) in dry methanol (25 mL) was added sodium phenylsulfinate (2.50 g, 15.2 mmol). After 2.5 h of reflux the mixture was concentrated under reduced pressure, the obtained residue was dissolved in EtOAc and the mixture was washed with water, brine, dried with Na2SO4, filtered and the filtrate was evaporated and purified by chromatography (50% EtOAc/Petroleum ether) to give 35 as a viscous oil: Yield (1.94 g, 74%);
1H NMR (400 MHz, CDCl3) δ 7.86 (d, J = 7.6 Hz, 2H), 7.64 (t, J = 7.6 Hz, 1 H), 7.54 (t, J = 7.6 Hz, 2H), 6.51 (s, 1H), 5.92(s, 1H), 4.17(s, 2H), 4.01(q, J = 7.2 Hz, 2H), 1.17(t, J = 7.2 Hz, 3H); 13C NMR (400 MHz, CDCl3) 164.73, 138.38, 133.86, 133.33, 129.11, 129.04, 128.77, 61.48, 57.52, 14.00.

에틸-(2-페닐술포메틸)-아크릴레이트 준비 용품 및 원자재

원자재

준비 용품

에틸-(2-페닐술포메틸)-아크릴레이트 공급 업체

공급자	전화	이메일	국가	제품 수	이점
RR Scientific LLC	+86-13917743231	sales@rrscientific.com	United States	878	58
ChengDu SinoStandards Bio-Tech Co.,Ltd. ，	028-83243028 19136088901	sinostandards@163.com	China	4983	58
R.R Scientific, LLC.	15010167677	zhiyuu1218@163.com	China	876	58

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