발네물린

발네물린
발네물린 구조식 이미지
카스 번호:
101312-92-9
한글명:
발네물린
동의어(한글):
발네물린
상품명:
VALNEMULIN
동의어(영문):
VALNEMULIN;supplier valnemulin;Acetic acid,[[2-[[(2R)-2-amino-3-methyl-1-oxobutyl]amino]-1,1-dimethylethyl]thio]-,(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-ylester;2-[[2-[[(2R)-2-Amino-3-methyl-1-oxobutyl]amino]-1,1-dimethylethyl]thio]acetic Acid (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-Ethenyldecahydro-5-hydroxy-4,6,9,10- tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl Ester;Acetic acid, 2-[[2-[[(2R)-2-amino-3-methyl-1-oxobutyl]amino]-1,1-dimethylethyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester
CBNumber:
CB4364450
분자식:
C31H52N2O5S
포뮬러 무게:
564.82
MOL 파일:
101312-92-9.mol

발네물린 속성

녹는점
140-143°C
끓는 점
672.7±55.0 °C(Predicted)
밀도
1.13±0.1 g/cm3(Predicted)
저장 조건
2-8°C
용해도
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
물리적 상태
고체
산도 계수 (pKa)
14.65±0.70(Predicted)

안전

발네물린 C화학적 특성, 용도, 생산

개요

Valnemulin is a broad-spectrum pleuromutilin antibiotic that binds to peptidyl transferase in the 50S ribosomal subunit. It has been used in veterinary medicine to treat swine diseases including, B. hyodysenteriae and M. hyopneumoniae.

화학적 성질

White to Off-White Solid

용도

Valnemulin is a semi-synthetic pleuromutilin prepared by sequential reaction of pleuromutilin tosylate with 2-amino-1,1-dimethylethylthiol, coupling the free amine with a protected valine and then deprotection to provide the final product. Valnemulin is a broad spectrum antibiotic used to control gastrointestinal infections in animals and shows no cross resistance to other antibiotic classes. Like all the pleuromutilins, valnemulin inhibits protein synthesis by binding to domain V of 23S RNA.

발네물린 준비 용품 및 원자재

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