N,N-Dimethylglycine
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N,N-Dimethylglycine 속성
- 녹는점
- 178-182 °C(lit.)
- 끓는 점
- 193.35°C (rough estimate)
- 밀도
- 1 g/cm3
- 굴절률
- 1.4674 (estimate)
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- 메탄올(약간 용해됨), 물(약간 용해됨)
- 산도 계수 (pKa)
- 9.89(at 25℃)
- 물리적 상태
- 결정성 분말
- 색상
- 흰색에서 약간 노란색
- 수용성
- 녹는
- 감도
- Hygroscopic
- Merck
- 14,3244
- BRN
- 1700261
- InChIKey
- FFDGPVCHZBVARC-UHFFFAOYSA-N
- CAS 데이터베이스
- 1118-68-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn,Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 22-36/37/38 | ||
안전지침서 | 24/25-36/37-26 | ||
WGK 독일 | 3 | ||
RTECS 번호 | MB9865000 | ||
F 고인화성물질 | 3 | ||
TSCA | Yes | ||
위험 등급 | IRRITANT | ||
HS 번호 | 29224999 | ||
독성 | rat,LD50,oral,> 650mg/kg (650mg/kg),BEHAVIORAL: ATAXIABLOOD: CHANGES IN SPLEENGASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA",Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 199, 1992. | ||
기존화학 물질 | KE-11416 |
N,N-Dimethylglycine C화학적 특성, 용도, 생산
개요
N,N-Dimethylglycine (DMG) is a N-methylated product of the amino acid glycine. It is found in beans and liver. It can be formed from trimethylglycine upon the loss of one of its methyl groups. It is also a byproduct of the metabolism of choline. When DMG was first discovered, it was referred to as vitamin B16, but, unlike true B vitamins, deficiency of DMG in the diet does not lead to any ill-effects meaning it does not meet the definition of a vitamin. It is used in comparative analysis with other N-methylated glycines. N,N-Dimethylglycine is used in the development of glycine-based ionic liquids and emulsifiers, and as a substrate to identify, differentiate and characterize amino acid methyltransferase(s). It is potentially useful as a biomarker of protein degradation in COPD patients.화학적 성질
white to slightly yellow crystalline powder용도
N,N-Dimethylglycine is used as an athletic performance enhancer and immunostimulant. It is also used in the treatment of autism, epilepsy and mitochondrial disease. It is also employed as a biomarker of protein degradation in chronic obstructive lung disease (COPD) patients. Further, it is used as a substrate to identify, differentiate and characterize amino acid methyltransferase. It plays an important role for the development of glycine-based ionic liquids and emulsifiers.제조 방법
N,N-Dimethylglycine is commercially available as the free form amino acid, and as the hydrochloride salt [2491-06-7 ]. DMG may be prepared by the alkylation of glycine via the Eschweiler–Clarke reaction. In this reaction, glycine is treated with aqueous formaldehyde in formic acid that serves as both solvent and reductant. Hydrochloric acid is added thereafter to give the hydrochloride salt. The free amino acid may been obtained by neutralization of the acid salt, which has been performed with silver oxide.H2NCH2COOH + 2 CH2O + 2 HCOOH →(CH3)2NCH2COOH + 2 CO2 + 2 H2O.
정의
ChEBI: N,N-dimethylglycine is an N-methylglycine that is glycine carrying two N-methyl substituents. It has a role as a human metabolite, a Daphnia magna metabolite and a mouse metabolite. It is a N-methyl-amino acid and a member of N-methylglycines. It is a tautomer of a N,N-dimethylglycine zwitterion.주요 응용
N, N-dimethylglycine (DMG) is a tertiary amino acid that naturally occurs as an intermediate metabolite in choline-to-glycine metabolism. It has been suggested for use as an athletic performance enhancer, immunostimulant, and a treatment for autism, epilepsy, or mitochondrial disease . Published studies on the subject have shown little to no difference between DMG treatment and placebo in autism spectrum disorders.일반 설명
N,N-Dimethylglycine is a type of quaternary ammonium compound which exhibits a variety of biological effects.N,N-Dimethylglycine 준비 용품 및 원자재
원자재
디메틸아미노아세토니트릴
N-메틸히드록실아민 수화염화물
N,N-DIMETHYLGLYCINE METHYL ESTER
DIETHYL 2-(DIMETHYLAMINO)MALONATE
디메틸글리신에틸에스테르
N N-DIMETHYLAMINOACETIC ACID SODIUM SALT
N-METHYL-2-DIMETHYLAMINOACETOHYDROXAMIC ACID
글리옥실산수화물
글리신
사르코신
준비 용품
N,N-Dimethylglycine 공급 업체
글로벌( 455)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
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Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 |
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Hebei Fengjia New Material Co., Ltd | +86-0311-87836622 +86-17333973358 |
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Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 |
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Sigma Audley | +86-18336680971 +86-18126314766 |
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Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 |
admin@zlchemi.com | China | 3002 | 58 |
Hebei Mojin Biotechnology Co.,Ltd | +8613288715578 |
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Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 16914 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21668 | 55 |