Tivozanib (hydrate)
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Tivozanib (hydrate) 속성
- 저장 조건
- Store at -20°C
- 용해도
- ≤25mg/ml in DMSO;30mg/ml in dimethyl formamide
- 물리적 상태
- 결정질 고체
안전
Tivozanib (hydrate) C화학적 특성, 용도, 생산
개요
Tivozanib is an orally available, selective VEGFR inhibitor with IC50 values of 0.21, 0.16, and 0.24 nM for VEGFR1, VEGFR2, and VEGFR3, respectively. It can also inhibit c-Kit and PDGFRβ with IC50 values of 1.63 and 1.72 nM, respectively. When administered to athymic rats, tivozanib was shown to decrease the microvessel density within tumor xenografts and attenuate VEGFR2 phosphorylation levels in tumor endothelium. It also displays antitumor activity against a wide variety of human tumor xenografts, including lung, breast, colon, ovarian, pancreas, and prostate cancer.Tivozanib (hydrate) 준비 용품 및 원자재
원자재
준비 용품
Tivozanib (hydrate) 공급 업체
글로벌( 12)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| BOC Sciences | -- |
info@bocsci.com | USA | 0 | 65 |
| DC Chemicals | 021-58447131 13564518121 |
sales@dcchemicals.com | China | 9412 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 |
order@med-bio.cn | China | 8141 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 |
customer_service@efebio.com | China | 8739 | 58 |
| ApexBio Technology | -- |
sales@apexbt.com | United States | 6254 | 58 |