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Remibrutinib

Remibrutinib 구조식 이미지

카스 번호:: 1787294-07-8

상품명:: Remibrutinib

동의어(영문):: LOU064;LOU-064;REMIBRUTINIB;Remibrutinib (LOU064);Btk,Inhibitor,inhibit,Remibrutinib,Bruton tyrosine kinase;N-(3-(6-Amino-5-(2-(N-methylacrylamido)ethoxy)pyrimidin-4-yl)-5-fluoro-2-methylphenyl)-4-cyclopropyl-2-fluorobenzamide;N-(3-{5-[2-(Acryloyl-methyl-amino)-ethoxy]-6-amino-pyrimidin-4-yl}-5-fluoro-2-methyl-phenyl)-4-cyclopropyl-2-fluoro-benzamide;N-[3-[6-Amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluorobenzamide;Benzamide, N-[3-[6-amino-5-[2-[methyl(1-oxo-2-propen-1-yl)amino]ethoxy]-4-pyrimidinyl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluoro-

CBNumber:: CB44675356

분자식:: C27H27F2N5O3

포뮬러 무게:: 507.53

MOL 파일:: 1787294-07-8.mol

속성

안전

용도

공급 업체 45

Remibrutinib 속성

끓는 점: 634.8±55.0 °C(Predicted)

밀도: 1.332±0.06 g/cm3(Predicted)

저장 조건: Store at -20°C

용해도: DMSO: 125 mg/mL (246.29 mM)

물리적 상태: Solid

산도 계수 (pKa): 11.67±0.70(Predicted)

색상: White to off-white

안전

Remibrutinib C화학적 특성, 용도, 생산

개요

Remibrutinib, is a potent and orally active bruton tyrosine kinase (BTK) inhibitor with an IC₅₀ value of 1 nM. Remibrutinib inhibits BTK activity with an IC₅₀value of 0.023 μM in blood. Remibrutinib has the potential for Chronic urticaria (CU) treatment.

Remibrutinib 준비 용품 및 원자재

원자재

준비 용품

Remibrutinib 공급 업체

글로벌( 45)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Suzhou ARTK Medchem Co., Ltd.	+8618168183658	sales1@artkmedchem.com	China	39009	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	orders@jknbiochem.com	China	4692	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	sales@chemhifuture.com	China	4399	58
Shanghai XingMo Biotechnology Co., Ltd.	13524779951	2075692521@qq.com	China	310	55
Shanghai Hope Chem Co., Ltd.，	+21-18501659228 18501659228	info@hope-chem.com	China	442	55
Bayee Biotech (Anqing) Co., Ltd.	0556-0556-5032306 18917961636	wtx@bayeebio.com	China	253	61