MMP-8억제제I

MMP-8억제제I
MMP-8억제제I 구조식 이미지
카스 번호:
236403-25-1
한글명:
MMP-8억제제I
동의어(한글):
MMP-8억제제I
상품명:
MMP-8 INHIBITOR I
동의어(영문):
MMP 8-I;MMP-8 INHIBITOR I;MMP-8 Inhibitor I (Matrix Metalloproteinase-8 Inhibitor I);(3R)-(+)-[2-(4-METHOXYBENZENESULFONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-3-HYDROXAMATE];3-Isoquinolinecarboxamide, 1,2,3,4-tetrahydro-N-hydroxy-2-[(4-methoxyphenyl)sulfonyl]-, (3R)-
CBNumber:
CB4710190
분자식:
C17H18N2O5S
포뮬러 무게:
362.4
MOL 파일:
Mol file

MMP-8억제제I 속성

저장 조건
-20°C
용해도
클로로포름(약간 용해됨), 메탄올(약간 용해됨)
물리적 상태
고체
물리적 상태
단단한 모양
색상
황백색에서 밝은 노란색까지

안전

MMP-8억제제I C화학적 특성, 용도, 생산

개요

MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM. This inhibitor does not target the activities of other MMPs in vitro. MMP-8 cleaves interstitial collagens and has exhibited activity in atherosclerotic plaques, angiogenesis, and stem cell mobilization. Additionally, MMP-8 expression is observed in normal mammary epithelial cells, whereas a loss of expression is observed in human ductal carcinoma in situ and the deletion of MMP-8 accelerates tumor onset in a mouse model of aggressive breast cancer.

용도

MMP 8-I is a matrix metalloproteinase 8 inhibitor. Matrix metalloproteinases are involved with tight junction protein degradation in endothelial cells.

MMP-8억제제I 준비 용품 및 원자재

원자재

준비 용품


MMP-8억제제I 공급 업체

글로벌( 18)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Alpha Biopharmaceuticals Co., Ltd
+86-15542445688
sales@alabiochem.com China 888 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439
sales@nextpeptide.com China 19915 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501
product@acmec-e.com China 33350 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52927 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11289 58
Alabiochem Tech.Co., Ltd. 0512-58900862 400-0707518
sales@alabiochem.com China 997 59
Alabiotech Inc. 001-619-354-5251
sales@alabiotech-e.com United States 972 60
Alpha Biopharmaceuticals Co., Ltd 0411-39042497
sales@alphabiopharm.com China 1951 58
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939
shenlinxing@macklin.cn China 29803 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 8739 58

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