1,3-DICHLORO-5-[(1E)-2-(4-CHLOROPHENYL)ETHENYL]-BENZENE

1,3-DICHLORO-5-[(1E)-2-(4-CHLOROPHENYL)ETHENYL]-BENZENE 구조식 이미지
카스 번호:
688348-25-6
상품명:
1,3-DICHLORO-5-[(1E)-2-(4-CHLOROPHENYL)ETHENYL]-BENZENE
동의어(영문):
PDM 2;PDM-2;PDM2;PDM 2;688348-25-6;(E)-1,3-Dichloro-5-(4-chlorostyryl)benzene;1,3-dichloro-5-[(E)-2-(4-chlorophenyl)ethenyl]benzene;1,3-DICHLORO-5-[(1E)-2-(4-CHLOROPHENYL)ETHENYL]-BENZENE;Benzene, 1,3-dichloro-5-[(1E)-2-(4-chlorophenyl)ethenyl]-;inhibit,Aryl Hydrocarbon Receptor,PDM2,PDM-2,PDM 2,Inhibitor,AhR
CBNumber:
CB4739467
분자식:
C14H9Cl3
포뮬러 무게:
283.58
MOL 파일:
688348-25-6.mol

1,3-DICHLORO-5-[(1E)-2-(4-CHLOROPHENYL)ETHENYL]-BENZENE 속성

끓는 점
394.2±42.0 °C(Predicted)
밀도
1.360±0.06 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 2 mg/ml
물리적 상태
결정성 고체
색상
White to off-white

안전

1,3-DICHLORO-5-[(1E)-2-(4-CHLOROPHENYL)ETHENYL]-BENZENE C화학적 특성, 용도, 생산

개요

The aryl hydrocarbon receptor (AhR) is a ligand-dependent intracellular transcription factor whose ligands include some of the most infamous xenobiotics, including dioxin, benzo[a]pyrene, and numerous polyaromatics from soot and coal tar. PDM 2 is an analog of resveratrol acting as a potent and selective aryl hydrocarbon receptor (AhR) antagonist, with a Ki of 1.2 nM. PDM 2 is inactive as a ligand for the estrogen receptor even at 100 μM. As AhR knockout mice are insensitive to the carcinogenic effects of classical AhR ligands, PDM 2 is a potential therapeutic for the treatment for dioxin and other aryl hydrocarbon poisonings.

1,3-DICHLORO-5-[(1E)-2-(4-CHLOROPHENYL)ETHENYL]-BENZENE 준비 용품 및 원자재

원자재

준비 용품


1,3-DICHLORO-5-[(1E)-2-(4-CHLOROPHENYL)ETHENYL]-BENZENE 공급 업체

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