ARV-471

ARV-471 구조식 이미지
카스 번호:
2229711-68-4
상품명:
ARV-471
동의어(영문):
ARV-471;Vepdegestrant;Vepdegestrant(ARV-471);3-(4-hydroxy-6-methyl-1-oxoisoindolin-2-yl)piperidine-2,6-dione;(S)-3-(5-(4-((1-(4-((1R,2S)-6-Hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)phenyl)piperidin-4-yl)methyl)piperazin-1-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione;oral,Inhibitor,breast cancer,PROTAC,E3 ligase,inhibit,hetero-bifunctional,ubiquitylation,ARV-471,PROTACs,Estrogen Receptor/ERR,ARV 471,estrogen receptor,ARV471,proteasome;2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-[4-[[1-[4-[(1R,2S)-1,2,3,4-tetrahydro-6-hydroxy-2-phenyl-1-naphthalenyl]phenyl]-4-piperidinyl]methyl]-1-piperazinyl]-2H-isoindol-2-yl]-, (3S)-
CBNumber:
CB48816045
분자식:
C45H49N5O4
포뮬러 무게:
723.9
MOL 파일:
2229711-68-4.mol

ARV-471 속성

밀도
1.275±0.06 g/cm3(Predicted)
용해도
DMSO : 110 mg/mL (151.95 mM; Need ultrasonic)
물리적 상태
Solid
산도 계수 (pKa)
10.36±0.60(Predicted)
색상
White to off-white

안전

ARV-471 C화학적 특성, 용도, 생산

용도

ARV-471 is a best-in-class, orally active estrogen receptor (ER) PROTAC degrader. It is developed for the research of breast cancer.

ARV-471 준비 용품 및 원자재

원자재

준비 용품


ARV-471 공급 업체

글로벌( 42)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581
sales@chemhifuture.com China 3136 58
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32760 60
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830
figo.gao@foxmail.com China 7621 58
TargetMol Chemicals Inc.
+1-781-999-5354
support@targetmol.com United States 19973 58
Xilinglab Co., Ltd.
+8618381337976
bd@xilinglab.com China 86 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57511 58
Tianjin Lanshu Pharmaceutical Technology Co., Ltd 15210678165
hanyachao@163.com China 10 58
ChemFuture PharmaTech (Jiangsu) Ltd 5108538618
suger.wang@chemfuture.com China 832 65
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 17702719238 17702719238
sales@sun-shinechem.com China 950 64
TargetMol Chemicals Inc. 021-021-33632979 15002134094
marketing@targetmol.com China 7846 58

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