P-METHOXYPHENYLACETIC ACID;4MPAA;HOMOANISIC ACID;ASISCHEM D13364;HOMO-P-ANISIC ACID;RARECHEM AL BO 0133;p-Anisylacetic acid;4-Methoxyphenylaceti;p-Methioxy-toluicacid;4-Methoxyphenylacetic
4-Methoxyphenylacetic Acid is a compound that was found from microbial phenolic metabolites in human feces after the consumption of gin, red wine and dealcholized red wine.
정의
ChEBI: A monocarboxylic acid that is phenylacetic acid carrying a 4-methoxy substituent. It is used as an intermediate for pharmaceuticals and other organic synthesis. It has been found to inhibit the germination of cress and lettuce seeds.
일반 설명
Pale yellow or off white colored flakes. Severely irritates skin and eyes. May be toxic by ingestion.
건강위험
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
화재위험
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.
Safety Profile
Moderately toxic by
ingestion and intraperitoneal routes.
Questionable carcinogen with experimental
neoplastigenic data. When heated to
decomposition it emits acrid smoke and
irritating fumes.
Purification Methods
Crystallise the acid from EtOH/water, EtOAc/pet ether (m 87o) or *C6H6/pet ether (m 84-86o). [Beilstein 10 III 431, 10 IV 544.] The acid chloride [4693-91-8] has M 184.6, b 143o/10mm, d 254