9-메톡시캄프토테신

9-메톡시캄프토테신
9-메톡시캄프토테신 구조식 이미지
카스 번호:
19685-10-0
한글명:
9-메톡시캄프토테신
동의어(한글):
9-메톡시캄프토테신
상품명:
9-methoxycamptothecin
동의어(영문):
product/154918;9-methoxycamptothecin;10-MethoxycaMptothecine;10 Methoxycamptothecin,Inhibitor,10Methoxycamptothecin,inhibit,10-Methoxycamptothecin;(4S)-4-Ethyl-4-hydroxy-9-methoxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;(4S)-4-Ethyl-4-hydroxy-9-methoxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;(4S)-9-Methoxy-4α-ethyl-4β-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione,4-ethyl-4-hydroxy-9-methoxy-, (4S)-;(S)-4-Ethyl-4-hydroxy-9-methoxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione
CBNumber:
CB51308407
분자식:
C21H18N2O5
포뮬러 무게:
378.38
MOL 파일:
19685-10-0.mol

9-메톡시캄프토테신 속성

녹는점
254-255℃
끓는 점
773.1±60.0 °C(Predicted)
밀도
1.50
저장 조건
4°C, protect from light
용해도
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
물리적 상태
Cryst.
산도 계수 (pKa)
11.21±0.20(Predicted)
색상
White to yellow

안전

9-메톡시캄프토테신 C화학적 특성, 용도, 생산

개요

A minor constituent of Mappia foetida Miers. The alkaloid yields pale yellow crystals when purified from CHC13-MeOH. It is laevorotatory with [α]24D - 77.5° (c 1.0, pyridine). The structure has been established by spectroscopic methods.

용도

10-Methoxycamptothecin is a Camptothecin (C175150) derivative used in the treatment of cancers. Used in the treatment of hyperproliferative diseases.

참고 문헌

Govindachari, Viswanathan., Phytochem., 11, 3529 (1972)
Govindachari, Viswanathan.,Ind. J. Chem., 10,453 (1972)

9-메톡시캄프토테신 준비 용품 및 원자재

원자재

준비 용품


9-메톡시캄프토테신 공급 업체

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