플루비아톨리드

플루비아톨리드
플루비아톨리드 구조식 이미지
카스 번호:
28115-68-6
한글명:
플루비아톨리드
동의어(한글):
플루비아톨리드
상품명:
pluviatolide
동의어(영문):
pluviatolide;trans-Pluviatolide;3α-(4-Hydroxy-3-methoxybenzyl)-4β-(1,3-benzodioxole-5-ylmethyl)-4,5-dihydrofuran-2(3H)-one;4,5-Dihydro-4β-[(1,3-benzodioxole-5-yl)methyl]-3α-(4-hydroxy-3-methoxybenzyl)furan-2(3H)-one;2(3H)-Furanone, 4-(1,3-benzodioxol-5-ylmethyl)dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4R)-;(3R,4R)-4-[(1,3-Benzodioxol-5-yl)methyl]-4,5-dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]furan-2(3H)-one
CBNumber:
CB51346359
분자식:
C20H20O6
포뮬러 무게:
356.37
MOL 파일:
28115-68-6.mol

플루비아톨리드 속성

저장 조건
Store at -20°C
용해도
DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
물리적 상태
고체
LogP
2.590 (est)

안전

플루비아톨리드 C화학적 특성, 용도, 생산

개요

Pluviatolide is a lignan that has been found in B. chinense and has diverse biological activities, including antioxidant, enzyme inhibitory, and antispasmodic properties. It scavenges ABTS and 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in cell-free assays (IC50s = 23.2 and 88.5 μM, respectively). Pluviatolide inhibits matrix metalloproteinase-7 (MMP-7) with an IC50 value of 260 μM. It decreases contractions induced by acetylcholine in isolated guinea pig ileum when used at concentrations of 30 and 100 μM.

정의

ChEBI: A butan-4-olide that is dihydrofuran-2(3H)-one which is substituted by a vanillyl group at position 3 and by a 3,4-methylenedioxybenzyl group at position 4 (the R,R stereoisomer).

플루비아톨리드 준비 용품 및 원자재

원자재

준비 용품


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