DL-6,8-티옥트 산
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DL-6,8-티옥트 산 속성
- 녹는점
- 60-62 °C
- 끓는 점
- 160-165 °C(lit.)
- 밀도
- 1.2888 (rough estimate)
- 굴절률
- 1.5200 (estimate)
- 인화점
- 160-165°C
- 저장 조건
- 2-8°C
- 용해도
- 에탄올: 50mg/mL
- 물리적 상태
- 결정 또는 결정성 분말
- 산도 계수 (pKa)
- 4.75±0.10(Predicted)
- 색상
- 노란색
- 수용성
- 0.9g/L(20℃)
- Merck
- 14,9326
- BRN
- 81853
- 안정성
- 안정적인. 강한 산화제와 호환되지 않습니다.
- InChIKey
- AGBQKNBQESQNJD-UHFFFAOYSA-N
- LogP
- 2.530 (est)
- CAS 데이터베이스
- 1077-28-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 22-20/21/22 | ||
안전지침서 | 37/39-26-24/25-36-36/37/39 | ||
WGK 독일 | 3 | ||
RTECS 번호 | JP1192000 | ||
HS 번호 | 29349990 | ||
유해 물질 데이터 | 1077-28-7(Hazardous Substances Data) |
DL-6,8-티옥트 산 C화학적 특성, 용도, 생산
개요
DL-화학적 성질
Light-Yellow Solid용도
(±)-α-Lipoic acid has been used in in vitro lipoylation studies and in the pyruvate dehydrogenase complex (PDC)-pyruvate dehydrogenase kinase (PDHK) functional assay. It has also been used to investigate its antioxidative effect on developing cerebellum of rats exposed to arsenic during postnatal period.일반 설명
Oxidized form. Has antioxidant properties. Growth factor for many bacteria and protozoa.Pharmaceutical Applications
Lipoic acid(ALA), also known as α-lipoic acid (alpha-lipoic acid) or thioctic acid, has the formula C8H14S2O2 and systematic name 5-(1,2-dithiolan-3-yl)pentanoic acid. It contains a disulfide group, which can be transformed in the body to a dithiol group.ALA has been on the market since the 1950s as a dietary supplement. It is a natural antioxidant usually made by the body. The advantage of ALA over other antioxidants such as vitamin C and E is that it is soluble both in water and in fat. Researchers in the former Soviet Union found that ALA can chelate mercury once it is transformed into the dithiol-containing compound. ALA can penetrate both the blood–brain barrier and the cell membrane and therefore would be a very interesting chelating agent. Nevertheless, there is much debate about its mode of action, side effects and effectiveness. Other antidotes, such as BAL and DMSA, are more efficient in the removal of heavy metals. ALA has not received FDA approval as a chelating agent, but it is still sold as a food supplement.
Purification Methods
It forms yellow needles from cyclohexane or hexane and has been distilled at high vacuum; and sublimes at ~90o and very high vacuum. It is insoluble in H2O but dissolves in alkaline solution. [Lewis & Raphael J Chem Soc 4263 1962, Soper et al. J Am Chem Soc 76 4109, Reed & Niu J Am Chem Soc 77 416 1955, Tsuji et al. J Org Chem 43 3606 1978, Calvin Fed Proc USA 13 703 1954.] The S-benzylisothiuronium salt has m 153-154o (evacuated capillary, from MeOH), 132-134o, 135-137o (from EtOH). The dand lforms have m 45-47.5o and [] D 23 ±113o (c 1.88, *C6H6) and have UV in MeOH with max at 330nm ( 140). [Beilstein 19/7 V 237.] The reduced form, (±)-6,8-dimercaptooctanoic acid, [7516-48-5] M 208.3, is a light yellow liquid which is sold in sealed ampoules.DL-6,8-티옥트 산 준비 용품 및 원자재
원자재
준비 용품
DL-6,8-티옥트 산 공급 업체
글로벌( 919)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Shandong Luning Pharmaceutical Co., Ltd. | +86-0546-6491488 +86-13305469775 |
sale@lntzkg.com | China | 40 | 58 |
Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 |
info@konochemical.com | China | 2995 | 58 |
Guangzhou TongYi biochemistry technology Co.,LTD | +8613073028829 |
mack@tongyon.com | China | 2996 | 58 |
XI'AN TIANGUANGYUAN BIOTECH CO., LTD. | +86-029-86333380 18829239519 |
sales06@tgybio.com | China | 918 | 58 |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 |
info@gihichemicals.com | China | 50000 | 58 |
Wuhan Quanjinci New Material Co.,Ltd. | +8615271838296 |
kyra@quanjinci.com | China | 1534 | 58 |
BINBO BIOLOGICAL CO.,LTD | +8618629063126 |
info@binbobiological.com | China | 346 | 58 |
Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 |
info@fortunachem.com | China | 5989 | 58 |
Beri Pharma Co., Ltd. | +8613417710166 |
sales@zhberi.com | China | 210 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 |
1022@dideu.com | China | 3320 | 58 |
DL-6,8-티옥트 산 관련 검색:
시트르산 DL-말산 아세트산 엽산 이소발레릴산 씨옥틱산 펜탄산 DL-6,8-티옥트 산
DIHYDROLIPOIC ACID
alpha-lipoic acid-NHS
Ascoric Acid
R-alpha-Lipoic acid tromethamine salt
Sodium thioctate
5-[(3S)-Dithiolan-3-yl]pentanoic acid
D,L-ALPHA-LIPOIC ACID-NHS
3-(5-[1,2]DITHIOLAN-3YL-PENTANOYLAMINO)-PROPYL-AMIDE
LIPOIC ACID, DL-ALPHA-(P)
{DL-THIOCTIC ACID (A-LIPOIC