1-메틸라데노신

1-메틸라데노신
1-메틸라데노신 구조식 이미지
카스 번호:
15763-06-1
한글명:
1-메틸라데노신
동의어(한글):
1-메틸라데노신
상품명:
1-METHYLADENOSINE
동의어(영문):
N1-Me-rA;N1-Me-Adenosine;1-METHYLADENOSINE;Adenosine, 1-methyl-;1-methyladenosine free base;N,6-Didehydro-1,6-dihydro-1-methyladenosine;(2R,3R,4R,5R)-2-(hydroxymethyl)-5-(6-imino-1-methyl-purin-9-yl)oxolane-3,4-diol;inhibit,1-Methyladenosine,1 Methyladenosine,Endogenous Metabolite,Inhibitor,1Methyladenosine;(2R,3R,4S,5R)-2-(6-Amino-1-methyl-1H-purin-9(2H)-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-imino-1-methyl-1,6-dihydro-9H-purin-9-yl)tetrahydrofuran-3,4-diol
CBNumber:
CB5187128
분자식:
C11H15N5O4
포뮬러 무게:
281.27
MOL 파일:
15763-06-1.mol
MSDS 파일:
SDS

1-메틸라데노신 속성

녹는점
>217°C (dec.)
끓는 점
655.4±65.0 °C(Predicted)
밀도
1.88±0.1 g/cm3(Predicted)
저장 조건
−20°C
용해도
DMSO (약간 용해됨), 물 (약간 용해됨,초음파처리)
물리적 상태
고체
물리적 상태
단단한 모양
산도 계수 (pKa)
13.24±0.70(Predicted)
색상
흰색에서 황백색까지
수소이온지수(pH)
8.8
최대 파장(λmax)
258 (pH 2);258 (pH 7);259,260~265 (pH 13)
안정성
흡습성, 감광성

안전

안전지침서 24/25
HS 번호 29389090

1-메틸라데노신 C화학적 특성, 용도, 생산

개요

1-Methyladenosine is a modified nucleoside generated by the processing of tRNA by methyltransferases. The urinary excretion of 1-methyladenosine is elevated in several forms of cancer, supporting its use as a biomarker in early detection. It can also be monitored in serum. Urinary levels of 1-methyladenosine also increase during active rheumatoid arthritis.

화학적 성질

White to off-white crystalline powder

용도

1-Methyl Adenosine is a modified adenosine molecule created through the processing of tRNA by methyltransferases. The presence seen to be elevated in the urinary excretion of cancer patients. Thus it may be an early diagnosis biomarker.

정의

ChEBI: A methyladenosine carrying a methyl substituent at position 1.

1-메틸라데노신 준비 용품 및 원자재

원자재

준비 용품


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