코르티코렐린양

코르티코렐린양 C화학적 특성, 용도, 생산

용도

Diagnostic aid(adrenocortical insufficiency); diagnostic aid (Cushing’s syndrome); hormone (corticotropin-releasing).

Biological Functions

The primary function of corticotropin-releasing factor (CRF), a hypothalamic 41-peptide, is the regulation of the release of adrenocorticotropin hormone (ACTH) from the anterior pituitary gland, which then stimulates the release of hydrocortisone from the adrenal gland. The human peptide (hCRF) and the similar sequence found in sheep (oCRF) have been prepared by synthesis. The ovine form of the hormone, however, has replaced the human form because of its longer half-life and greater potency; hCRF is no longer commercially available.
Usually, ACTH deficiency in humans is associated with a pituitary disorder rather than with a deficiency of CRF, and oCRF can be used to distinguish between pituitary hypersecretion of ACTH (Cushing's disease) and ectopic ACTH secretion, both of which are conditions that cause a hypersecretion of hydrocortisone. In the case of ectopic ACTH secretion, the administration of oCRF will elicit little to no response in the production of ACTH and hydrocortisone. Therefore, synthetic oCRF trifluoroacetate salt is marketed as a diagnostic agent for patients with ACTH dependent Cushing's syndrome.

코르티코렐린양 준비 용품 및 원자재

원자재

준비 용품

코르티코렐린양 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	16914	58
Cellmano Biotech Limited	0551-65326643 18156095617	info@cellmano.com	China	999	58
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42959	64
Cellmano Biotech Limited	0551-65326643 18156095617	info@cellmano.com	China	1011	55
Nanjing Peptide Biotech Ltd.	025-025-58361106-805-805 13082558573	liugang@njpeptide.com	China	9978	55
Nanjing Meihao Pharmaceutical Technology Co., Ltd.	meitaochem@126.com	meitaochem@126.com	China	19105	58
Gill polypeptide biopharmaceutical (dalian) co., LTD	021-61263455 13167021076	amy@glschina.com	China	8543	58
Nanjing Shizhou Biology Technology Co.,Ltd	13675144456	alan.chow@synzest.com	China	9471	58
Nanjing Yuanpeptide Biotech Co.，Ltd.	18168071971	support@yuan-peptide.com	China	2977	58
Chengdu Jinglin Biotechnology Co., Ltd.	17711399154	3211919385@qq.com	China	1815	58

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