디[3-데옥시-D-만노-옥툴로소닐]-지질A(aMMonuM염)
|
|
디[3-데옥시-D-만노-옥툴로소닐]-지질A(aMMonuM염) 속성
- 저장 조건
- -20°C
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- White to off-white
안전
디[3-데옥시-D-만노-옥툴로소닐]-지질A(aMMonuM염) C화학적 특성, 용도, 생산
용도
Kdo2-Lipid A (KLA) is a nearly homogeneous Re lipopolysaccharide (LPS) substracture with endotoxin activity equal to tha of native LPS. KLA is comparable to LPS and its activity is reduced by >10^3 in cells fro TLR-4 deficient mice.일반 설명
3-deoxy-D-manno-octulosonic acid (Kdo2-Lipid A) is the essential component of lipopolysaccharide in most Gram-negative bacteria and the minimal structural component to sustain bacterial viability. It serves as the active component of lipopolysaccharide to stimulate potent host immune responses through the complex of Toll-like-receptor 4 (TLR4) and myeloid differentiation protein 2 (MD2). Therefore, Kdo2-lipid A is an important stimulator for studying the mechanism of the innate immune system and for developing bacterial vaccine adjuvants. Kdo2 Lipid A/TLR4 antagonists can also be applied in anti-inflammatory interventions. Kdo2-lipid A, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagy. Kdo2-Lipid A has been used in animal atherosclerosis model.Biochem/physiol Actions
Kdo2-Lipid A might be useful to stimulate inflammatory response.디[3-데옥시-D-만노-옥툴로소닐]-지질A(aMMonuM염) 준비 용품 및 원자재
원자재
준비 용품
디[3-데옥시-D-만노-옥툴로소닐]-지질A(aMMonuM염) 공급 업체
글로벌( 26)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
Creative Enzymes | 1-516-855-7709 |
info@creative-enzymes.com | United States | 8748 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
Codow Chemical Co.,Ltd. | 18620099427 |
amy@howeipharm.com | China | 17698 | 55 |
Chengdu Dianchun Technology Co., Ltd | 400-1166-196 18502815961 |
cdhxsj@163.com | China | 14623 | 60 |
Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 |
3193328036@qq.com | China | 29786 | 68 |
Beijing Minruida Technology Co., Ltd. | 010-82387566 18001021521; |
sales@mreda.com.cn | China | 21450 | 58 |
BOC Sciences | 16314854226 |
inquiry@bocsci.com | United States | 9713 | 58 |
TargetMol Chemicals Inc. | 15002134094 |
marketing@targetmol.cn | China | 28091 | 58 |
SHANGHAI ZZBIO CO., LTD. | 13916577892 19921389125 |
tech@zzbioco.com | China | 12063 | 58 |