페닐붕산
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페닐붕산 속성
- 녹는점
- 216-219 °C(lit.)
- 끓는 점
- 265.9±23.0 °C(Predicted)
- 밀도
- 1.13±0.1 g/cm3(Predicted)
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- 클로로포름(약간 용해됨), DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 결정성 분말
- 산도 계수 (pKa)
- 8.83(at 25℃)
- 색상
- 흰색에서 황백색까지
- 수용성
- 10g/L(20℃)
- 감도
- Hygroscopic
- Merck
- 14,1068
- BRN
- 970972
- 안정성
- 흡습성
- InChIKey
- HXITXNWTGFUOAU-UHFFFAOYSA-N
- CAS 데이터베이스
- 98-80-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn,Xi,N | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22-36/37/38-20/21/22 | ||
| 안전지침서 | 22-24/25-36/37/39-26-36 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | CY8575000 | ||
| 위험 참고 사항 | Harmful | ||
| TSCA | Yes | ||
| 위험 등급 | IRRITANT, MOISTURE SENSITIVE | ||
| HS 번호 | 29310095 | ||
| 독성 | LD50 orl-rat: 740 mg/kg 14KTAK -,693,64 | ||
| 기존화학 물질 | 2004-3-2926 |
페닐붕산 C화학적 특성, 용도, 생산
물성
뜨거운 물, 유기 용제에 녹는다. 약한 산이고 알칼리와 염을 만든다. 알코올에 의해 에스테르를 만든다. 가열하면 쉽게 무수물이 된다. 산화되기 쉽고 공기에 의해 붕산 H3BO3가 얻어진다. 또 물과 끓여도 붕산이 된다.용도
이 제품은 백색 분말이며 의약 중간체로 사용됩니다.페닐 붕산 및 유도체 계열 제품은 신약 합성의 중요한 중간체로서 주로 사용됩니다.화학적 성질
white to light yellow crystal powder. Insoluble in water and benzene, easily soluble in ether and methanol. When exposed to air or under heating conditions, it is easy to dehydrate and form a three-molecular polymer.용도
Phenylboronic Acid is a compound used in organic synthesis of various pharmaceutical goods.Phenylboronic acid (PBA) and its derivatives can bind sugars and other diol compounds to form cyclic boronate esters. These esters bear negative charges. Due to this reaction, sugars can be detected by means of electrochemical and optical techniques.
PBA modified electrodes have been constructed as reagentless electrochemical sensors. There, PBA is absorbed on the electrode surface either as a self- assembled monolayer film ore a polymer thin film. Basically, for optical detection techniques for the detection of sugars, PBA is modified with a chromophore that should change its properties on reaction with a sugar.
Reaction of Phenylboronic acid with a sugar
정의
ChEBI: Phenylboronic acid is a member of boronic acids. It is functionally related to a boronic acid.일반 설명
Phenylboronic acid (PBA) is an organoboronic acid. It behaves as a molecular receptor that can attach to compounds containing cis-diol group. Microwave-assisted Suzuki coupling of aryl chlorides with phenylboronic acid in the presence of Pd/C (catalyst) and water (solvent) has been described. Palladium-catalyzed cross-coupling reaction of phenylboronicacid with haloarenes to afford biaryls has been reported.Safety Profile
Poison by intravenous andintraperitoneal routes. Moderately toxic by ingestion.Mildly toxic by skin contact. When heated to decomposition it emitsacrid smoke and irritating fumes.페닐붕산 준비 용품 및 원자재
원자재
준비 용품
페닐붕산 공급 업체
글로벌( 853)공급 업체
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