RYCMAAFECCXGHI-ILKKLZGPSA-N

RYCMAAFECCXGHI-ILKKLZGPSA-N 구조식 이미지
카스 번호:
159190-44-0
상품명:
RYCMAAFECCXGHI-ILKKLZGPSA-N
동의어(영문):
RYCMAAFECCXGHI-ILKKLZGPSA-N;LNIO dihydrochloride,L NIO dihydrochloride;(S)-5-Acetimidamido-2-aminopentanoic acid dihydrochloride;L-N-(1-Iminoethyl)ornithine, Dihydrochloride - CAS 159190-44-0 - Calbiochem
CBNumber:
CB53416708
분자식:
C7H16ClN3O2
포뮬러 무게:
209.67
MOL 파일:
159190-44-0.mol
MSDS 파일:
SDS

RYCMAAFECCXGHI-ILKKLZGPSA-N 속성

저장 조건
-20C
용해도
<24.61mg/ml in H2O
물리적 상태
흰색 고체
색상
Colorless to off-white
수용성
물에 100mM까지 용해됨

안전

RYCMAAFECCXGHI-ILKKLZGPSA-N C화학적 특성, 용도, 생산

용도

N5-(1-Iminoethyl)-L-ornithine Dihydrochloride is an inhibitor of nitric oxide synthase (NOS), an enzyme that catalyzes the conversion of L-arginine to L-citrulline and nitric oxide. It also improves cardiac function and microcirculation. N5-(1-Iminoethyl)-L-ornithine Dihydrochloride inhibits inducible NOS (iNOS). These enzymes play critical roles in a wide array of physiological and pathophysiological conditions such as blood pressure regulation, inflammation, and infection.

일반 설명

Cell permeable. Approximately five times more potent as an inhibitor of endothelial nitric oxide synthase (IC50 = 500 nM) than other arginine analogs, such as L-NAME (Cat. No. 483125) and L-NMMA (Cat. No. 475886). Inhibits acetylcholine induced relaxation of rat aorta rings (IC50 = 2 μM) and causes a dose-dependent increase in mean arterial blood pressure in the rat (EC50 = 19.5 mg/kg).

Biochem/physiol Actions

Cell permeable: yes

RYCMAAFECCXGHI-ILKKLZGPSA-N 준비 용품 및 원자재

원자재

준비 용품


RYCMAAFECCXGHI-ILKKLZGPSA-N 공급 업체

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