4-[(3-브로모페닐)아미노]-6-프로피오닐아미도퀴나졸린
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4-[(3-브로모페닐)아미노]-6-프로피오닐아미도퀴나졸린 속성
- 저장 조건
- -20°C
- 용해도
- DMF: 30 mg/ml; DMSO: 10 mg/ml; Ethanol: 1 mg/ml
- 물리적 상태
- 노란색 고체
- 색상
- Light yellow to yellow
안전
4-[(3-브로모페닐)아미노]-6-프로피오닐아미도퀴나졸린 C화학적 특성, 용도, 생산
개요
PD 174265 is a potent, cell-permeable inhibitor of the tyrosine kinase activity of the epidermal growth factor (EGF) receptor (IC50 = 0.45 nM). It is effective in cells, blocking tyrosine phosphorylation induced by either EGF or heregulin (IC50s = 39 and 220 nM, respectively). The action of PD 174265 is reversible, which makes it a useful tool for comparative studies with irreversible inhibitors of EGFR kinase activity.용도
PD 174265 is a potent, cell-permeable, reversible, and selective inhibitor of EGFR tyrosine kinase activity.일반 설명
A potent, cell-permeable, reversible, ATP-competitive and selective inhibitor of EGF receptor (EGFR) tyrosine kinase activity (IC50 = 450 pM). The reversible nature of this compound makes it a less effective antitumor agent than PD 168393 (Cat. No. 513033).효소 저해제
This substituted quinazoline (FWfree-base = 371.24 g/mol), also known as 4- [(3-bromophenyl)amino]-6-propionylamidoquinazoline, inhibits epidermal growth factor receptor (EGFR) protein-tyrosine kinase, IC50 = 0.45 nM. PD 174265 selectively targets and irreversibly inactivates the epidermal growth factor receptor tyrosine kinase through specific, covalent modification of a Cys-773. See also PD 1683934-[(3-브로모페닐)아미노]-6-프로피오닐아미도퀴나졸린 준비 용품 및 원자재
원자재
준비 용품
4-[(3-브로모페닐)아미노]-6-프로피오닐아미도퀴나졸린 공급 업체
글로벌( 53)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
Tianjin Kailiqi Biotechnology Co., Ltd. | 15076683720 |
klq@cw-bio.com | China | 4425 | 55 |
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 |
sales@glpbio.cn | China | 6870 | 58 |
BOC Sciences | -- |
info@bocsci.com | USA | 0 | 65 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 |
order@med-bio.cn | China | 8141 | 58 |
Energy Chemical | 021-58432009 400-005-6266 |
marketing@energy-chemical.com | China | 44941 | 58 |
Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 |
486064515@qq.com | China | 3433 | 58 |