ANTI-CDK4 C화학적 특성, 용도, 생산
용도
Monoclonal Anti-Cdk4 antibody was used in:
- immunoprecipitation of human melanoma cell line.
- immunofluorescence of fibrosarcoma cells.
- western blot analysis
- immunofluorescence
- immunohistochemistry
일반 설명
Cdk4 exists, in part, as a multi-protein complex with a D-type cyclin, proliferating cell nuclear antigen (PCNA) and a protein inhibitor, p21
Cip1. Cdk4 associates separately with p16, particularly in cells lacking a functional retinoblastoma protein.
Biochem/physiol Actions
In association with cyclins, cyclin-dependent kinases (CDKs) forms active kinase complexes which is responsible for regulating cell cycle progression in eukaryotic cells. Within the complexes, the CDKs serves a catalytic protein kinase activity. This catalytic activity is regulated by two mechanisms: protein phosphorylation and association of regulatory subunits.
ANTI-CDK4 준비 용품 및 원자재
원자재
준비 용품
