리토드린

리토드린
리토드린 구조식 이미지
카스 번호:
26652-09-5
한글명:
리토드린
동의어(한글):
리토드린
상품명:
RITODRINE
동의어(영문):
Lavopa;Premar;RITODRINE;ritodrina;Formoterol-d;RITODRINE USP/EP/BP;Phenoxybenzamine hydrochl;Ritodrine Impurity 2 (Ritodrine);(1R,2S)-2-(4-Hydroxyphenethylamino)-1-(4-hydroxyphenyl)-1-propanol;4-[(1R,2S)-1-Hydroxy-2-[2-(4-hydroxyphenyl)ethylamino]propyl]phenol
CBNumber:
CB5476882
분자식:
C17H21NO3
포뮬러 무게:
287.35
MOL 파일:
26652-09-5.mol

리토드린 속성

녹는점
88-90 °C
끓는 점
512.3±45.0 °C(Predicted)
밀도
1.213±0.06 g/cm3(Predicted)
산도 계수 (pKa)
pKa 9.0 (Uncertain)

안전

기존화학 물질 KE-20582

리토드린 C화학적 특성, 용도, 생산

개요

Ritodrine, 4-hydroxy-α-[1-[(4′-hydroxyphenethyl)amino]ethyl]benzylic alcohol (11.1.19), differs slightly from epinephrine, and in the given example only one hydroxyl group has been added to the aromatic ring of the phenylethylamino region of classic sympathomimetics. The second major difference between the examined series is the replacement of the traditionally terminal iso-propyl or tert-butylamine region with a p-hydroxyphenylethylamine. Finally, the third difference is the presence of a methyl group at the α-atom of the phenylethylamine region of sympathomimetics, which makes it similar to isoetharine.

용도

Ritodrine is a selective β2-adrenoreceptor stimulant, predominantly of the urino-genital system. It is used as a tocolytic agent for problems associated with premature miscarriages, and only in specialized medical facilities.

일반 설명

Ritodrine is a selective β2-agonist that wasdeveloped specifically for use as a uterine relaxant. Its uterineinhibitory effects are more sustained than its effects onthe cardiovascular system, which are minimal comparedwith those caused by nonselective β-agonists. The cardiovasculareffects usually associated with its administrationare mild tachycardia and slight diastolic pressure decrease.Usually, it is administered initially by intravenous infusionto stop premature labor and subsequently it may be givenorally.

Clinical Use

Ritodrine is a selective β2-agonist that is used exclusively for relaxing uterine muscle and inhibiting the contractions of premature labor. Terbutaline, in addition to its use as a bronchodilator, also has been used for halting the contractions of premature labor.

리토드린 준비 용품 및 원자재

원자재

준비 용품


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