Terevalefim

Terevalefim 구조식 이미지
카스 번호:
1070881-42-3
상품명:
Terevalefim
동의어(영문):
Terevalefim;Terevalefim(ANG-3777);(E)-3-(2-(thiophen-2-yl)vinyl)-1H-pyrazole;1H-Pyrazole, 3-[(1E)-2-(2-thienyl)ethenyl]-;3-[(E)-2-(thiophen-2-yl)ethenyl]-2H-pyrazole;ANG-3777,Terevalefim,injury,acute,inhibit,ANG 3777,AKI,kidney,ANG3777,transplantation,c-Met/HGFR,HGF,Inhibitor
CBNumber:
CB54868672
분자식:
C9H8N2S
포뮬러 무게:
176.24
MOL 파일:
1070881-42-3.mol

Terevalefim 속성

끓는 점
369.3±11.0 °C(Predicted)
밀도
1.318±0.06 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
DMSO : 100 mg/mL (567.41 mM; Need ultrasonic)
산도 계수 (pKa)
14.05±0.10(Predicted)
물리적 상태
Solid
색상
White to light brown

안전

Terevalefim C화학적 특성, 용도, 생산

개요

Terevalefim (ANG-3777) is a hepatocyte growth factor (HGF) mimetic that in preclinical and phase 2 studies has demonstrated the ability to activate the c-Met receptor and the pathways associated with that activation, improving renal function in induced-AKI in animals and long-term graft function occurring in renal transplantation recipients with signs of DGF[1-2].

Terevalefim 준비 용품 및 원자재

원자재

준비 용품


Terevalefim 공급 업체

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