네오카지노스타틴
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네오카지노스타틴 속성
- 녹는점
- 260° (dec)
- 저장 조건
- 2-8°C
- 물리적 상태
- Liquid
- 색상
- Colorless to light yellow
안전
| 독성 | LD50 in mice (mg/kg): 1050 orally, 0.96 i.v. (Toriyama) |
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네오카지노스타틴 C화학적 특성, 용도, 생산
개요
Neocarzinostatin was found in the culture broth of Streptomyces carzinostaticus by Ishida et al. of Tohoku University in 1957. It showed strong cytotoxicity against sarcoma 180 ascites, tumor cells, and leukemia SN36. Neocarzinostatin was found to be an acidic peptide of Mr 10700, consisting of 109 amino acid residues. Recently the principal agent of anticancer and antibacterial activity in neocarzinostatin was found to be a small molecular chromophore with the peptide component playing a role by stabilizing the chromophore in vivo. Neocarzinostatin is used to treat leukemia and gastric and pancreatic cancer.용도
Neocarzinostatin from Streptomyces carzinostaticus has been used:- as a DNA damaging agent to treat human fibroblast GM0637 cells
- as a radiomimetic antibiotic to induce DNA damage
- in combination with Vγ2Vδ2 T cells to determine the cytotoxicity in ovarian cancer cells
네오카지노스타틴 준비 용품 및 원자재
원자재
준비 용품
네오카지노스타틴 공급 업체
글로벌( 20)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 |
contact@trustwe.com | China | 5738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Zhejiang Huida Biotech Co., LTD | 008613515763466 8615669048680 |
wendy@huidabiotech.com | CHINA | 87 | 58 |
| T&W GROUP | 021-61551611 13296011611 |
contact@trustwe.com | China | 9900 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 |
3003855609@qq.com | China | 7887 | 56 |
| Chizhou Kailong Import and Export Trade Co., Ltd. | |
xg01_gj@163.com | China | 9503 | 50 |
| Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 |
psaitong@jm-bio.com | China | 12308 | 58 |
| Zhejiang Huida Biotech Co., LTD | 0571-89903882 13626641628 |
jiangnan@huidabiotech.com | China | 3657 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; |
psaitong@jm-bio.com | China | 29778 | 58 |