CP-154,526

CP-154,526 구조식 이미지
카스 번호:
157286-86-7
상품명:
CP-154,526
동의어(영문):
CP154;CP 154;CP-154;CP-154,526;N-butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-amine;N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine;7H-Pyrrolo[2,3-d]pyrimidin-4-amine,N-butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-;N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-aminehydrochloride
CBNumber:
CB5675292
분자식:
C23H32N4
포뮬러 무게:
364.53
MOL 파일:
157286-86-7.mol

CP-154,526 속성

끓는 점
423.5±45.0 °C(Predicted)
밀도
1.06
저장 조건
Desiccate at +4°C
산도 계수 (pKa)
6.97±0.30(Predicted)

안전

CP-154,526 C화학적 특성, 용도, 생산

용도

A selective, non-peptide antagonist of corticotropin releasing factor receptors (CRF1). It blocks CRF-induced adenylate cyclase activation and attenuates activation of the HPA axis by CRF. It displayed anxiolytic-like activity in the rat elevated plus-maze test; brain penetrant.

생물학적 활성

Selective, non-peptide CRF 1 receptor antagonist (K i values are 2.7 and > 10000 nM for CRF 1 and CRF 2 receptors respectively). Blocks CRF-induced adenylate cyclase activation (K i = 3.7 nM) and attenuates activation of the HPA axis by CRF. Displays anxiolytic-like activity in the rat elevated plus-maze test; brain penetrant.

CP-154,526 준비 용품 및 원자재

원자재

준비 용품


CP-154,526 공급 업체

글로벌( 19)공급 업체
공급자 전화 이메일 국가 제품 수 이점
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 19892 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
3bsc@sina.com China 15848 69
LETOPHARM LIMITED +86-21-5821 5861
sales@letopharm.com China 2384 58
TargetMol Chemicals Inc. 4008200310
marketing@tsbiochem.com China 23963 58

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