3-요오드-L-티로신
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3-요오드-L-티로신 속성
- 녹는점
- 210 °C (dec.)(lit.)
- 밀도
- 1.7280 (estimate)
- 저장 조건
- -20°C
- 용해도
- 묽은 산성 수용액: 가용성
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 끓는 점
- 391.0±42.0 °C(Predicted)
- 산도 계수 (pKa)
- 2.21±0.20(Predicted)
- 색상
- 흰색에서 황백색까지
- 감도
- Light Sensitive
- Merck
- 14,5047
- BRN
- 2941266
- 안정성
- 흡습성
- InChIKey
- UQTZMGFTRHFAAM-ZETCQYMHSA-N
- CAS 데이터베이스
- 70-78-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
3-요오드-L-티로신 C화학적 특성, 용도, 생산
화학적 성질
White Solid용도
3-iodo-l-tyrosine is used in the inhibition of tyrosine hydroxylase. 3-iodo-L-tyrosine is used in the rapid induction of prolactin secretion.정의
ChEBI: The monoiodotyrosine that is L-tyrosine carrying an iodo-substituent at position C-3 of the benzyl group.일반 설명
Iodotyrosine coupled with di-iodotyrosine results in the synthesis of 3,5,3′-tri-iodothyronine (T3) or 3,3′,5′-tri-iodothyronine (rT3).Purification Methods
Likely impurities are tyrosine, diiodotyrosine and iodide. Crystallise it by dissolving it in concentrated ammonia (~200mg in ~20mL), evaporate to ~5mL and NH4Cl is added to pH4.5—5.0. After a few hours at 0o, the amino acid crystallises in needles. It is filtered off, washed with a little ice-cold H2O and dried in a vacuum. Alternatively dissolve it in dilute ammonia at room temperature, then add dilute acetic acid to pH 6. Store it at 0o. Recrystallisation of ~250mg from H2O (~5mL) removes any diiodotyrosine. It is an inhibitor of tyrosine hydroxylase with a Ki of ~500nM. [Harrington & Rivers Biochem J 38 320 1944, Rivers Chem & Ind (London) 21 1956, Beilstein 14 III 1562, 14 IV 1562.]3-요오드-L-티로신 준비 용품 및 원자재
원자재
준비 용품
3-요오드-L-티로신 공급 업체
글로벌( 244)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Suzhou Ryan Pharmachem Technology Co.,Ltd. | +86-512-68780025 +8618962125825 |
sales@ryanchem.com | China | 137 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 18628 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2931 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
SIMAGCHEM CORP | +86-13806087780 |
sale@simagchem.com | China | 17367 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 |
sales@tnjchem.com | China | 34571 | 58 |
GL Biochem (Shanghai) Ltd. | +86-021-61263370 +86-18901917034 |
CHINA | 3904 | 58 | |
GL Biochem(Binhai) Ltd. | +86-021-61263370 +8615301650015 |
wuqiuyan@glschina.com | China | 2975 | 58 |
3-요오드-L-티로신 관련 검색:
3-요오드-L-티로신 티록신
REVERSE T3
3,5-Diiodo-L-thyronine
3,3',5-Triiodo-L-thyronine
3,3',5-TRIIODOTHYROPROPIONIC ACID
Thyroxine-4-hydroxy-3,5-diiodophenyl Ether DISCONTINUED
3,5-DIIODO-4'-(4-HYDROXYPHENOXY)BENZOIC ACID
N-ForMyl Thyroxine
3,5,3',5'-Tetraiodo Thyroaldehyde
3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID
4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzeneacetaMide
3,5,3',5'-Tetraiodo Thyrolactic Acid
3,3',5-TRIIODOTHYROACETIC ACID
O-(4-hydroxy-3-iodophenyl)-3-iodo-L-tyrosine
Liothyronine IMpurity E
Levothyroxine impurity E
Sodium levothyroxine