HUMAN PDGF-BB
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HUMAN PDGF-BB 속성
- 저장 조건
- -20°C
- 물리적 상태
- 동결건조된 분말
안전
위험품 표기 | Xi | ||
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위험 카페고리 넘버 | 36/38 | ||
안전지침서 | 26 | ||
WGK 독일 | 3 |
HUMAN PDGF-BB C화학적 특성, 용도, 생산
용도
Platelet-Derived Growth Factor-BB human has been used :- As a growth supplement in proximal tubule and glomerular explant cell culture
- In three-dimensional scaffold preparation
- To study the effect of brivanib on growth factor signaling pathways
- In transwell migration assay
일반 설명
Platelet-derived growth factor (PDGF) is expressed as homo and heterodimers : PDGF-AB FDGF-AA, PDGF-BB, PDGF-CC and PDGF-DD. The PDGF gene is highly conserved mapped to human chromosome 7p22.3. The active form of Pdgf exists as disulfide-linked dimers. It consists of cystine-knot-fold growth factor domain, which is highly conserved, except for the N-terminal prodomain, which shows variation in length among the isoforms.Biochem/physiol Actions
The three naturally occurring PDGFs (platelet-derived growth factors); PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Heterozygous mutation in PDGFB is associated with primary familial brain calcification. It is also associated with angiogenesis for osteogenesis. PDGFB induces migration of endothelial progenitor cells and mesenchymal stem cells.HUMAN PDGF-BB 준비 용품 및 원자재
원자재
준비 용품
HUMAN PDGF-BB 공급 업체
글로벌( 88)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 |
Cecilia@youngshechem.com | China | 2345 | 58 |
Chengdu Jinglin Biotechnology Co., Ltd. | 17711399154 |
3211919385@qq.com | China | 1815 | 58 |
GL Biochem (Shanghai) Ltd | 21-61263452 13641803416 |
ymbetter@glbiochem.com | China | 9981 | 64 |
Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 |
info@hanhongsci.com | China | 42959 | 64 |
Chemsky (shanghai) International Co.,Ltd | 021-50135380 |
shchemsky@sina.com | China | 15421 | 60 |
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 |
3193328036@qq.com | China | 29786 | 68 |
Chengdu Youngshe Chemical Co., Ltd. | +86-17380623303 +86-17380623303 |
Caroline@youngshechem.com | China | 4886 | 58 |
Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com |
meitaochem@126.com | China | 19105 | 58 |
Shanghai Kanglang Biotechnology Co., Ltd. | 021-61998208 18217752821 |
sales@klbio.cn | China | 9618 | 58 |