bucumolol hydrochloride

bucumolol hydrochloride 구조식 이미지
카스 번호:
36556-75-9
상품명:
bucumolol hydrochloride
동의어(영문):
CS 359;Bucumarol;Bucumalol;Bucumarol (HCl);bucumolol hydrochloride;dl-Bucumolol hydrochloride;8-(2-Hydroxy-3-tert-butylaminopropoxy)-5-methylcoumarin hydrochloride;DL-5-Methyl-8-(2-hydroxy-3-tert-butylaminopropoxy)coumarin hydrochloride;(+-)-5-Methyl-8-(2-hydroxy-3-tert-butylaminopropoxy)coumarin hydrochloride
CBNumber:
CB5875270
분자식:
C17H23NO4.ClH
포뮬러 무게:
341.833
MOL 파일:
36556-75-9.mol

bucumolol hydrochloride 속성

녹는점
226-228° (dec)

안전

독성 LD50 in male, female mice (mg/kg): 676, 692 orally; 33.1, 31.6 i.v. (Oshima)

bucumolol hydrochloride C화학적 특성, 용도, 생산

Originator

Bucumarol,Sankyo,Japan,1982

Manufacturing Process

A mixture of 3 g of 8-(2-hydroxy-3-chloropropoxy)-5-methyl coumarin, 4.3 g of t-butylamine and 60 ml of ethanol is heated at 100°C in a sealed tube for 15 hours. The reaction mixture is concentrated under reduced pressure to dryness. The residue is recrystallized from a mixture of ethanol and ether to give 2.1 g of the desired product melting at 226° to 228°C (with decomposition).
In practice it is usually used as hydrochloride.

Therapeutic Function

Beta-adrenergic blocker

bucumolol hydrochloride 준비 용품 및 원자재

원자재

준비 용품


bucumolol hydrochloride 공급 업체

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