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AG 957

AG 957 구조식 이미지

카스 번호:: 140674-76-6

상품명:: AG 957

동의어(영문):: AG 957;NSC 654705;TYRPHOSTIN 957;TYRPHOSTIN AG 957;LAVENDUSTIN C ANALOG;4-AMINO-N-(2,5-DIHYDROXYBENZYL)METHYL BENZOATE;METHYL-4-[N-(2',5'-DIHYDROXYBENZYL)AMINO]BENZOATE;Benzoic acid, 4-[[(2,5-dihydroxyphenyl)methyl]amino]-, methyl ester;Lavendustin C Analog, Methyl-4-[N-(2μ,5μ-dihydroxybenzyl)amino]benzoate;paxillin,NSC654705,c-Abl,Bcr-Abl,lipopolysaccharide,Tyrphostin AG-957,integrins,leukemia,tyrosine,Tyrphostin AG 957,hematopoiesis,AG-957,NSC-654705,AG 957,NSC 654705,AG957,Tyrphostin AG957,kinase,BCR/ABL,inhibit,cytoskeleton,Inhibitor,Chronic,myelogenous

CBNumber:: CB6100142

분자식:: C15H15NO4

포뮬러 무게:: 273.28

MOL 파일:: Mol file

속성

안전

용도

공급 업체 43

AG 957 속성

끓는 점: 504.2±45.0 °C(Predicted)

밀도: 1.337±0.06 g/cm3(Predicted)

저장 조건: −20°C

용해도: DMSO: 용해될 수 있다

물리적 상태: 결정질 고체

산도 계수 (pKa): 10.30±0.43(Predicted)

색상: Off-white to light brown

안전

안전지침서	22-24/25
WGK 독일	3

AG 957 C화학적 특성, 용도, 생산

개요

Tyrphostins are tyrosine phosphorylation inhibitors that act by inhibiting tyrosine kinases. AG957 is a tyrphostin that targets transforming Bcr-Abl fusion proteins (p185^Bcr-Abl, p210^Bcr-Abl), as well as normal c-Abl (IC₅₀s = 4.3, 1, and 7.1 μM, respectively, for human proteins). It also inhibits epidermal growth factor receptor (IC₅₀ = 0.25 μM). As the constitutively-active 210 kDa Bcr-Abl fusion protein commonly occurs in chronic myelogenous leukemia (CML) cells, AG957 is commonly used to study Bcr-Abl signaling in the CML K562 cell line. AG957 is also used to study signaling through c-Abl.

용도

Tyrphostin AG 957 is a potent tyrosine kinase inhibitor. Also, it causes metabolic alterations in K562 cells. It is a COVID19-related research product.

AG 957 준비 용품 및 원자재

원자재

준비 용품

AG 957 공급 업체

글로벌( 43)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Spectrum Chemical Manufacturing Corp.	021-021-021-67601398-809-809-809 15221380277	marketing_china@spectrumchemical.com	China	9664	60
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66099280 17798518460	cfzhang@aikonchem.com	China	19918	55
AdooQ BioScience, LLC	+1 (866) 930-6790	info@adooq.com	United States	2784	58
BOC Sciences	16314854226	info@bocsci.com	United States	9926	65
Shanghai CR Corporation Limited	021-80270511; 4006653949	fred.wen@crcorporation.cn	China	10047	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Shanghai Kaiwei Chemical Technology Co., Ltd.	021-58461859 15821823057	service@aiviche.com	China	49323	58

AG 957 관련 검색:

TYRPHOSTIN AG 879 TYRPHOSTIN AG 1296 TYRPHOSTIN B56 TYRPHOSTIN AG 1024 LAVENDUSTIN C