3,5-dihydroxy-3-methyl-Pentanoic acid
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3,5-dihydroxy-3-methyl-Pentanoic acid 속성
- 저장 조건
- 2-8°C
- 용해도
- DMSO에 용해됨
- 끓는 점
- 364.1±32.0 °C(Predicted)
- 밀도
- 1.263±0.06 g/cm3(Predicted)
- 녹는점
- 151-152 °C(Solv: benzene (71-43-2))
- 산도 계수 (pKa)
- 4.33±0.10(Predicted)
- 물리적 상태
- Solid
- 색상
- White to off-white
- Concentration
- 0.1 mCi/ml
- Specific Activity
- 10-20 Ci/mmol
- Solvent
- Ethanol:0.15N NH4OH (1:1)
안전
| WGK 독일 | 3 | ||
|---|---|---|---|
| 유해 물질 데이터 | 150-97-0(Hazardous Substances Data) |
3,5-dihydroxy-3-methyl-Pentanoic acid C화학적 특성, 용도, 생산
용도
Precursor in the biosynthesis of cholesterol. Occurs in equilibrium with the d-lactone정의
Anorganic acid, it is an intermediate in the biosyn-thesis of squalene, cholesterol, and coenzyme q inplants and animals.Biosynthesis
Mevalonic acid is the primary precursor of an the terpenoids and steroids biosynthesised by plants. It is derived from acetyl CoA through the intermediate formation of acetoacetyl CoA and 3-hydroxy-3-methylglutaryl CoA (HMG CoA), these reactions being catalysed by acetyl CoA acetyltransferase and HMG CoA synthase, respectively. Reduction of HMG CoA, catalysed by HMG CoA reductase, gives mevalonic acid.
Before the pathway can continue, mevalonic acid must be catalytically phosphorylated by ATP and mevalonic acid kinase. Mevalonic acid kinase activity has been detected in many plants and has been found to be inhibited by such products of the acetate-mevalonate pathway as geranyl, farnesyl, geranylgeranyl and phytyl pyrophosphates. Thus, phosphorylation of mevalonic acid is a primary point at which control of terpenoid and steroid biosynthesis operates. Phosphorylation leads first to the mono- and then to the pyrophosphate. The second phosphorylation is catalysed by phosphomevalonate kinase.
3,5-dihydroxy-3-methyl-Pentanoic acid 준비 용품 및 원자재
원자재
준비 용품
3,5-dihydroxy-3-methyl-Pentanoic acid 공급 업체
글로벌( 20)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 |
1022@dideu.com | China | 3882 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32165 | 58 |
| TargetMol Chemicals Inc. | |
support@targetmol.com | United States | 38632 | 58 |
| Shanghai Macklin Biochemical Co.,Ltd. | 15221275939 15221275939 |
shenlinxing@macklin.cn | China | 16166 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51456 | 80 |
| Beijing OKA biological technology co., LTD | 010-010-010-62971590 18548936886 |
jack@oka-vip.com | China | 6897 | 58 |
| Guangdong wengjiang Chemical Reagent Co., Ltd. | 0751-2815688 13927872512 |
3007421951@qq.com | China | 10057 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 |
marketing1@energy-chemical.com | China | 44808 | 58 |
| TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 24647 | 58 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 18621169109 |
market03@meryer.com | China | 27987 | 58 |