Ferrous Bisglycinate

Ferrous Bisglycinate 속성

Ferrous Bisglycinate C화학적 특성, 용도, 생산

개요

Ferrous Bisglycinate, also known as ferrous glycinate, is an iron (II) chelate with an iron to glycine ratio of 1:2. It has an octahedral structure with two water molecules and two chelated glycinate ions coordinated to the central ferrous iron. Ferrous glycinate (processed with citric acid) also contains citric acid. It is manufactured by reaction of reduced iron with glycine in the presence of citric acid. The resulting product is spray dried without prior removal of the citric acid. The substance is highly hygroscopic and may contain water in variable amounts.

용도

Ferrous Bisglycinate is an iron-amio acid chelate. In this the iron is protected from the action of absorption inhibitors by being bound to the amino acid and glycine.
Ferrous bisglycinate is the major amino acid chelate produced commercially, although ferrous trisglycinate and ferric glycinate are also available. A patented ferrous bisglycinate compound, manufactured by Albion Laboratories, Utah, USA, has been used in most published studies. The chelate is reported to be formed by two glycine molecules combining with ferrous iron in a double heterocyclic ring structure. Evidence would suggest that iron is protected from inhibitors by the structure, since iron absorption is one to 3.5 times higher than from ferrous sulfate when added to bread rolls and milk products containing inhibitors such as phytate and calcium. Ferrous bisglycinate is more bioavailable than ferrous trisglycinate.

부작용

Ferrous Bisglycinate is a novel amino acid iron chelate that is more bioavailable and has fewer gastrointestinal (GI) adverse effects than iron salts. Adverse effects such as constipation, diarrhoea, stomach cramps or upset stomach may occur with Ferrous Bisglycinate. However, usually these effects are temporary and can recover on their own. Iron may cause your faeces to become darker; this effect is harmless. In addition, in the event of a severe allergic reaction to the drug, you need to stop taking it immediately and contact your doctor.

Synthesis

600kg water is added in 1500L reactor, 150kg glycine, 1.5kg carbonyl iron dust, and heating is added under agitation. Stir for 20 minutes to 65°C, then add 550kg ferrous sulfate heptahydrates, 37.5kg maltodextrins, 0.3kg silica, 78°C reaction 30 minutes, reaction complete. Reaction solution sieves heat filtering with 100 mesh stainless sheets of steel, and the filtrate is dried with a pressure spray drying tower, obtained To yellowish-brown green powder Ferrous Bisglycinate 490kg.

참고 문헌

[1] Adelia C Bovell-Benjamin, Lindsay H Allen, Fernando E Viteri. “Iron absorption from ferrous bisglycinate and ferric trisglycinate in whole maize is regulated by iron status123.” American Journal of Clinical Nutrition 71 6 (2000): Pages 1503-1509.
[2] JORDIE A J FISCHER. The effects of oral ferrous bisglycinate supplementation on hemoglobin and ferritin concentrations in adults and children: a systematic review and meta-analysis of randomized controlled trials.[J]. Nutrition reviews, 2023, 81 8: 904-920. DOI:10.1093/nutrit/nuac106.

Ferrous Bisglycinate 준비 용품 및 원자재

원자재

준비 용품

Ferrous Bisglycinate 공급 업체

공급자	전화	이메일	국가	제품 수	이점
SHIJIAZHUANG DONGHUA JINLONG CHEMICAL CO.,LTD.	0311-66619688 15632114516	donghuajinlong@glycine.com.cn	China	14	58
Hubei Xinkang Pharmaceutical Chemical Co., Ltd	027-027-59308705 18871579363	1248680011@qq.com	China	9265	58
Hebei Liwellso Biotech Co.,Limited	0318-8678112; 15803189002	287996538@qq.com	China	28	58
SUZHOU YINGKE BIOTECHNOLOGY CO.,LTD.	62896201 13806138270	sales@szykbio.com	China	20	58
Hebei Lihua Biotechnology Co. , Ltd.	15127018080	3119446261@qq.com	China	484	58
Jiaoda Rising Weinan Chemical Technology Co.,Ltd.	13992360862	718510010@qq.com	China	30	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	94588	76
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	45000	61
Adamas Reagent, Ltd.	4006009262 13023226327	hmj@titansci.com	China	14098	59
Sichuan Kulinan Technology Co., Ltd	400-1166-196 18981987031	cdhxsj@163.com	China	11674	57

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