엘로칼시톨

엘로칼시톨
엘로칼시톨 구조식 이미지
카스 번호:
199798-84-0
한글명:
엘로칼시톨
동의어(한글):
엘로칼시톨
상품명:
ELOCALCITOL
동의어(영문):
BXL 628;Ro 26-9228;ELOCALCITOL;Ellocalciferol;(1R,3E,5S)-3-[(2E)-2-[(3aS,7aS)-1-[(E,2S)-6-ethyl-6-hydroxyoct-4-en-2-yl]-7a-methyl-3a,5,6,7-tetrahydro-3H-inden-4-ylidene]ethylidene]-5-fluoro-4-methylidenecyclohexan-1-ol;Cyclohexanol, 3-[(2E)-2-[(3aS,7aS)-1-[(1S,3E)-5-ethyl-5-hydroxy-1-methyl-3-hepten-1-yl]-3,3a,5,6,7,7a-hexahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-5-fluoro-4-methylene-, (1R,3Z,5S)-
CBNumber:
CB61509111
분자식:
C29H43FO2
포뮬러 무게:
442.65
MOL 파일:
199798-84-0.mol
MSDS 파일:
SDS

엘로칼시톨 속성

끓는 점
568.3±50.0 °C(Predicted)
밀도
1.05±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
Ethanol:20.0(Max Conc. mg/mL);45.18(Max Conc. mM)
물리적 상태
결정성 고체
산도 계수 (pKa)
14.04±0.40(Predicted)
색상
White to off-white

안전

엘로칼시톨 C화학적 특성, 용도, 생산

개요

BXL-628 is an analog of vitamin D3 that has diverse biological activities. It increases death of androgen-stimulated human benign prostatic hyperplasia (BPH) cells via induction of apoptosis in a dose-dependent manner. In vivo, BXL-628 completely inhibits androgen-stimulated prostate overgrowth in a rat model of BPH. It reduces expression of IL-13 and IgE/mast cell-derived protease 1 (MMCP1) and decreases edema and leukocyte infiltration in the bladder wall in a mouse model of allergen-induced interstitial cystitis. BXL-628 also reduces the number of adherent endometrial stromal cells and decreases the total weight of endometrial lesions in a mouse model of endometriosis. Formulations containing BXL-628 are under clinical investigation for the treatment of BPH.

엘로칼시톨 준비 용품 및 원자재

원자재

준비 용품


엘로칼시톨 공급 업체

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