Pachymic acid
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Pachymic acid 속성
- 녹는점
- 300 °C(Solv: methanol (67-56-1); acetone (67-64-1))
- 끓는 점
- 612.2±55.0 °C(Predicted)
- 밀도
- 1.10±0.1 g/cm3(Predicted)
- 저장 조건
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- 용해도
- 메탄올(약간 용해됨), 피리딘(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 4.65±0.10(Predicted)
- 색상
- 흰색에서 황백색까지
- 안정성
- 흡습성
안전
Pachymic acid C화학적 특성, 용도, 생산
용도
Pachymic Acid is a natural triterpene extract which suppresses invasiveness of pancreatic cancer cells through the downregulation of MMP-7.Anticancer Research
Extracted from Poria cocos, pachymic acid (PA) is a tri-terpenoid (a lanostanetype), which is reported to have anticancerous properties. NCI-H460 and NCI-H23cells, the lung cancer cell lines, were studied for the effect of pachymic acid.Expression of a major UPR target gene-regulated protein, CHOP, was upregulatedresulting in cell apoptosis after PA treatment. It was discovered that ROS inhibitorsblocked the ER stress activation induced by PA. The results indicated that ROSproduction is also regulated by PA in lung cancer cells (Cheng et al. 2015; Jun et al.2015). As per the studies conducted on MIA PaCa-2 and PANC-1 cell lines,PA-induced apoptosis in pancreatic cancer cell resistant to gemcitabine wasdependent on in vivo and in vitro activation of ER stress. PA can be exploited for itsanticancer effects for treatment of pancreatic cancer resistant to chemotherapy(Cheng et al. 2015).Pachymic acid 준비 용품 및 원자재
원자재
준비 용품
Pachymic acid 공급 업체
글로벌( 218)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 |
qinhe02@xaltbio.com | China | 1000 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21673 | 55 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
Chengdu Greenpure Biopharma CO.,Ltd | +8618283602253 |
jancyzheng@gcgreenpure.com | China | 952 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29897 | 58 |
Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 |
scglp@glp-china.com | CHINA | 1824 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 |
info@konochemical.com | China | 2995 | 58 |
Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 |
sales@pioneerbiotech.com | China | 3000 | 58 |
Pachymic acid 관련 검색:
아세트산 시트르산 엽산 글리신 이소올레익산
CHLOROPHOSPHONAZO III
Ascoric Acid
(CIS)-8-METHYLNON-6-ENOIC ACID
6-decenoic acid
DIHYDROLANOSTEROL
CITRONELLIC ACID
(S)-(-)-3,7-DIMETHYL-6-OCTENOIC ACID
(+)-P-MENTH-1-EN-9-OL
10-NONADECENOIC ACID
2,2,4,6,6-PENTAMETHYL-3-HEPTENE
2-CYCLOPENTYL HEXANOIC ACID
O-Acetylpachymic acid-25-o1
Pachymic acid