2-MONOPALMITIN

2-MONOPALMITIN 구조식 이미지
카스 번호:
23470-00-0
상품명:
2-MONOPALMITIN
동의어(영문):
2-MONOOLEIN;2-Monopalmitoylglycerol;2-Palmitoyl-rac-glycerol;2-O-Palmitoylglycerol;2-Hexadecanoylglycerol;Glyceryl 2-monopalmitate;2-O-Hexadecanoylglycerol;2-O-Palmitoyl-L-glycerol;2-Monohexadecanoylglycerol;2-monopalmitoylglycerol (C16:0)
CBNumber:
CB6222338
분자식:
C19H38O4
포뮬러 무게:
330.5
MOL 파일:
23470-00-0.mol
MSDS 파일:
SDS

2-MONOPALMITIN 속성

녹는점
68-70°C
끓는 점
387.92°C (rough estimate)
밀도
0.9708 (rough estimate)
굴절률
1.4434 (estimate)
저장 조건
−20°C
용해도
클로로포름(약간 용해됨), 에틸아세테이트(약간 용해됨), 메탄올(약간 용해됨)
용해도
클로로포름(약간), 에틸아세테이트(약간), 메탄올(약간)에 용해됨
산도 계수 (pKa)
13.54±0.10(Predicted)
물리적 상태
Solid
색상
흰색에서 황백색까지
BRN
1796692

안전

위험품 표기 Xi
위험 카페고리 넘버 43
안전지침서 36/37
WGK 독일 3

2-MONOPALMITIN C화학적 특성, 용도, 생산

개요

2-Arachidonoyl glycerol (2-AG; ) is an endogenous agonist of the CB1 and CB2 cannabinoid receptors. 2-Palmitoyl glycerol is a fatty acid ester that does not bind directly to cannabinoid receptors, nor inhibit adenylyl cyclase, but rather potentiates the activity of 2-AG (and other endocannabinoids) to bind to CB1 and CB2 and inhibit adenylyl cyclase. This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release. 2-Palmitoyl glycerol and related endogenous fatty acid derivatives have been shown to interact with endocannabinoids in the modulation of pain sensitivity.

화학적 성질

White Solid

용도

A biomarker of metabolic responses to hepatotoxicants and carcinogens.

정의

ChEBI: A 2-monoglyceride where the acyl group is hexadecanoyl (palmitoyl).

생물학적 활성

Endogenous fatty acid glycerol ester that enhances activity of 2-arachidonylglycerol ((5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic acid,2-hydroxy-1-(hydroxymethyl)ethyl ester ). Does not bind to CB 1 or CB 2 cannabinoid receptors, but potentiates the apparent binding of 2-AG and increases its ability to inhibit adenylyl cyclase. Enhances in vivo cannabinoid effects of 2-AG following combined administration with 2-linoleoylglycerol.

2-MONOPALMITIN 준비 용품 및 원자재

원자재

준비 용품


2-MONOPALMITIN 공급 업체

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