(17ξ,20ξ,22ξ,25ξ)-3β-Hydroxy-28-methylveratraman-6(5H)-one C화학적 특성, 용도, 생산
개요
The bulbs of Korolkowia sewerzowii also yield this steroidal alkaloid which is
precipitated by the addition of C6H6 to a petroleum ether extract of the mixed
alkaloids. The base has [α]
D - 84° (c 0.9, CHC13) and forms crystalline salts,
e.g. the hydrobromide, m.p. 289-290°C; the perchlorate, m.p. 244-SoC; isothiocyanate, m.p. 264-SoC; oxime, m.p. 200-1 DC; methiodide, m.p. 244-SoC
and semicarbazone, m.p. 190°C after softening at 160°C. The O-acetyl derivative
forms a perchlorate, m.p. 178-9°C.
LiAIH4 or hydrogenation over Pt yields dihydrokorseving, m.p. 218-9°C;
[α]
D - 87° (c 0.16, MeOH) which gives a diacetyl derivative, m.p. l33-4°C.
Chromic acid oxidation furnishes korsevinone forming a perchlorate, m.p. 240°C
after crystallization from H20. The structure of the alkaloid has been determined
from mass spectrometry, NMR, ultraviolet and infrared spectroscopy
참고 문헌
Nuriddinov, Yunusov., Khim. Prir. Soedin., 3, 398 (1967)
(17ξ,20ξ,22ξ,25ξ)-3β-Hydroxy-28-methylveratraman-6(5H)-one 준비 용품 및 원자재
원자재
준비 용품
