C8-HSL

C8-HSL 구조식 이미지
카스 번호:
147852-84-4
상품명:
C8-HSL
동의어(영문):
OHL;C8-HSL;Octanoyl-L-hoMoserine lactone;(3R)-3-(2-Oxononyl)Oxolan-2-One;N-OCTANOYL-L-HOMOSERINE LACTONE;N-[(3S)-2-oxooxolan-3-yl]octanamide;(S)-N-(2-Oxotetrahydrofuran-3-yl)octanamide;C8-HSL, OHL, N-Octanoyl-L-hoMoserine lactone;N-Octanoyl-L-homoserine lactone >=96% (HPLC);N-[(3S)-Tetrahydro-2-oxo-3-furanyl]octanamide
CBNumber:
CB62456373
분자식:
C12H21NO3
포뮬러 무게:
227.3
MOL 파일:
147852-84-4.mol
MSDS 파일:
SDS

C8-HSL 속성

녹는점
134-135 °C
끓는 점
448.1±34.0 °C(Predicted)
밀도
1.04±0.1 g/cm3(Predicted)
저장 조건
-20°C
용해도
DMF: 25 mg/ml; DMF:PBS(pH7.2) 1:2: 0.3 mg/ml; DMSO: 20 mg/ml
물리적 상태
결정성 고체
산도 계수 (pKa)
14.83±0.20(Predicted)
색상
White to off-white
optical activity
[α]/D -28±3°, c = 0.2 in methanol
BRN
8148282

안전

WGK 독일 3

C8-HSL C화학적 특성, 용도, 생산

용도

Octanoyl-L-homoserine lactone is an active quorum sensing modulator first recognised in Yersinia pseudotuberculosis. Octanoyl-L-homoserine lactone and other acylhomoserine lactones have been detected in hundreds of bacterial species and, while the homologues vary between species and strains, the homoserine lactones are the major chemical modulators of within and between cell communication and regulation. The most significant variable defining the function of the homoserine lactone is the length of the acyl chain, with shorter chains displaying opposing actions to the longer chains.

일반 설명

N-Octanoyl-L-homoserine lactone (C8-HSL) is a N-acyl homoserine lactone (N-acyl-HSL). It is highly nonpolar.

Biochem/physiol Actions

N-Octanoyl-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-Acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, colonization, chemical defense and cell to cell communication among bacteria; for reviews see. AHLs are released as oligopeptides in Gram positive bacteria and as quorum signal in Gram negative bacteria. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs, and a research focus for the prevention of biofilm formation.

C8-HSL 준비 용품 및 원자재

원자재

준비 용품


C8-HSL 공급 업체

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