ChemicalBook >제품 카탈로그 >제약 중간체>헤테로 사이 클릭 화합물>피리딘 화합물>디 히드로 피리딘>(S)-Ketorolac

(S)-Ketorolac

(S)-Ketorolac 구조식 이미지

카스 번호:: 66635-92-5

상품명:: (S)-Ketorolac

동의어(영문):: Ketorolac S-IsoMer;(S)-Ketorolac ISO 9001：2015 REACH;Ketorolac impurity 2/Ketorolac S-Isomer;Phosphorousacid,tris(1,5-dimethylethyl)ester;1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-, (1S)-

CBNumber:: CB62485724

분자식:: C15H13NO3

포뮬러 무게:: 255.27

MOL 파일:: 66635-92-5.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 62

(S)-Ketorolac 속성

녹는점: 160-167?C

끓는 점: 493.2±40.0 °C(Predicted)

밀도: 1.33±0.1 g/cm3(Predicted)

저장 조건: Refrigerator

용해도: Chloroform: Slightly; Ethanol: >1mg/ml; Methanol: Slightly

물리적 상태: 결정성 고체

산도 계수 (pKa): 4.29±0.20(Predicted)

색상: White to off-white

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

그림문자(GHS):

신호 어:

Danger

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H301	삼키면 유독함	급성 독성 물질 - 경구	구분 3	위험		P264, P270, P301+P310, P321, P330,P405, P501

예방조치문구:

P264	취급 후에는 손을 철저히 씻으시오.
P264	취급 후에는 손을 철저히 씻으시오.
P270	이 제품을 사용할 때에는 먹거나, 마시거나 흡연하지 마시오.
P301+P310	삼켰다면 즉시 의료기관(의사)의 진찰을 받으시오.
P405	밀봉하여 저장하시오.
P501	...에 내용물 / 용기를 폐기 하시오.

(S)-Ketorolac C화학적 특성, 용도, 생산

개요

(S)-Ketorolac is a non-selective COX inhibitor and non-steroidal anti-inflammatory drug (NSAID; IC₅₀s = 0.1 and 2.7 μM for COX-1 and COX-2, respectively). (S)-Ketorolac is approximately twice as potent as the racemic mixture and 60 times more potent than (R)-ketorolac in a rat pain assay. (S)-Ketorolac is cleared from rat kidney and liver more quickly than (R)-ketorolac. Formulations containing ketorolac have been used to manage postoperative pain as well as an ophthalmic solution to treat ocular pain and inflammation.

화학적 성질

Off-White Solid

용도

(S)-Ketorolac is the S-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.

정의

ChEBI: A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has S configuration. While (S)-ketorolac is a COX1 and COX2 inhibitor, both enantiomers exhibit analgesic effects. Racemic ketorolac, known s mply as ketorolac, is used (mainly as the tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.

(S)-Ketorolac 준비 용품 및 원자재

원자재

준비 용품

(S)-Ketorolac 공급 업체

글로벌( 62)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23556	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9030	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	25502	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10522	58
CR Corporation Lomited		fred.wen@crcorporation.cn	CHINA	12069	58
Hebei Miaoyin Technology Co.,Ltd	+86-17367732028 +86-17367732028	kathy@hbyinsheng.com	China	3582	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58

(S)-Ketorolac 관련 검색:

Ketorolac Impurity 48 rac Ketorolac 6-Benzoyl IsoMer 5-Benzoyl-2,3-Dihydro-Lh-Pyrrolizme-L,L-DicarboxyiicAcid,KetoralacTromethamine 2,2'-BIPYRROL Ketorolac Related Compound A (20 mg) (5-benzoyl-N-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)-2,3-dihydro-1H-pyrrolizine-1-carboxamide) 1-Descarboxy Ketorolac Ketorolac EP IMpurity G Ketorolac Impurity 31 1-Keto Ketorolac (R)-(+)-Ketorolac Ketorolac Impurity 24 (5-chloro-1H-pyrrol-2-yl)-phenylmethanone 4-HYDROXY KETOROLAC Ketorolac Impurity 43 Ethyl 2-(1H-pyrrol-2-yl)acetate 3-BENZOYLPYRROLE Ketorolac Related Compound B (20 mg) (5-benzoyl-2,3-dihydro-1H-pyrrolizin-1-ol) Ketorolac tromethamine