플라스미노젠

플라스미노젠
플라스미노젠 구조식 이미지
카스 번호:
9001-91-6
한글명:
플라스미노젠
동의어(한글):
플라스미노젠
상품명:
PLASMINOGEN
동의어(영문):
PROFIBRINOLYSIN;PLASMINOGEN, HUMAN;HUMAN GLU-PLASMINOGEN;PLASMINOGEN USP/EP/BP;PROFIBRINOLYSIN, HUMAN;GLU-PLASMINOGEN (HUMAN);PLASMA TRYPSINOGEN, HUMAN;PLASMINOGEN, HUMAN PLASMA;PLASMINOGEN, GLU-TYPE, HUMAN;plasminogen from horse plasma
CBNumber:
CB6257448
분자식:
NULL
포뮬러 무게:
0
MOL 파일:
Mol file
MSDS 파일:
SDS

플라스미노젠 속성

저장 조건
-20°C
물리적 상태
동결건조된 분말

안전

위험품 표기 B,Xi
위험 카페고리 넘버 36/37/38
안전지침서 26-36
WGK 독일 3
F 고인화성물질 10-21

플라스미노젠 C화학적 특성, 용도, 생산

용도

Plasminogen is a single-chain glycoprotein found in human plasma and extracellular fluid. Certain activators, such as tissue plasminogen activator (tPA), convert plasminogen to its active form, plasmin. Plasminogen has been used to study its conversion into plasmin.

일반 설명

The plasminogen (PLG) gene is mapped to human chromosome 6q26. Plasminogen protein has a molecular weight of ?90kDa. It is composed of Pan-apple domain at the N-terminal, five kringle domains and serine protease domain at its C-terminal.

Biochem/physiol Actions

Plasminogen is the inactive precursor of the protease plasmin. Plasminogen is activated by the action of either tissue plasminogen activator (tPA), which primarily activates the fibrinolytic (thrombolytic) activity of plasmin, or urokinase plasminogen activator (uPA), which is associated with extracellular matrix remodeling and cell migration. Plasmin cleaves fibrin/fibrinogen and blood coagulation factors V/Va and VIII/VIIIa. It activates matrix metalloproteinases by cleaving the inactive proenzymes. It is also involved in the activation of some growth factors, such as vascular endothelial growth factor (VEGF) and transforming growth factor β (TGF-β).

플라스미노젠 준비 용품 및 원자재

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