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CP-31398이염산염수화물 C화학적 특성, 용도, 생산
용도
CP-31398 dihydrochloride hydrate has been used as a p53 stabilizer:
to evaluate its effects on the upregulation of miRNA in human neuroblastoma cells
to study its effects on arsenic trioxide (ATO) stabilization of p53 folding
to study its effects on regulation of miR-34 in PC12 cells
Biochem/physiol Actions
CP-31398 is a styryl quinazoline that functions in preserving the activity of p53 as a tumor suppressor and transcription factor. The DNA-binding activity and apoptosis functionality of the p53 are restored by CP-31398. CP-31398 exhibits therapeutic effects against liver, skin, pancreatic, and colon cancers.
