가스트린방출펩티드,인간

가스트린방출펩티드,인간
가스트린방출펩티드,인간 구조식 이미지
카스 번호:
93755-85-2
한글명:
가스트린방출펩티드,인간
동의어(한글):
가스트린방출펩티드,인간
상품명:
GASTRIN RELEASING PEPTIDE, HUMAN
동의어(영문):
GRP;LGALSL;HSPC159;GRP (HUMAN);PubChem ID: 23185015;Galectin-related protein;GASTRIN RELEASING PEPTIDE;GASTRIN RELEASING AGENT, HUMAN;M.W. 2859.40 C130H204N38O31S2;VPLPAGGGTVLTKMYPRGNHWAVGHLM-NH2
CBNumber:
CB6271275
분자식:
C130H204N38O31S2
포뮬러 무게:
2859.38
MOL 파일:
93755-85-2.mol

가스트린방출펩티드,인간 속성

밀도
1.46±0.1 g/cm3(Predicted)
저장 조건
−20°C
물리적 상태
가루
색상
White to off-white
수용성
Soluble to 1 mg/ml in water
시퀀스
H-Val-Pro-Leu-Pro-Ala-Gly-Gly-Gly-Thr-Val-Leu-Thr-Lys-Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2

안전

WGK 독일 3

가스트린방출펩티드,인간 C화학적 특성, 용도, 생산

용도

GRP (gastrin releasing peptide) has been used for absorption/neutralization of anti-GRP antibody prior to the tyramide signal amplification (TSA) procedure.

일반 설명

GRP (gastrin releasing peptide) is the mammalian homolog of bombesin (BBS) and functions as a mitogen for multiple cancers, such as neuroblastoma. It is a ligand for GRPR (GRP receptor) and is expressed in a subtype of peptidergic dorsal root ganglion neurons.

Biochem/physiol Actions

GRP (gastrin releasing peptide) functions as an autocrine growth factor for nueroblastoma. It facilitates cell survival in PI3K/AKT (phosphatidylinositol-3-kinase/ v-Akt murine thymoma viral oncogene)-mediated manner and cell proliferation and angiogenesis in neuroblastoma. This peptide is involved in the release of gastrin and the control of gastric acid secretion and motor function. In patients with atopic dermatitis, the serum levels of this peptide are linked with pruritus.

가스트린방출펩티드,인간 준비 용품 및 원자재

원자재

준비 용품


가스트린방출펩티드,인간 공급 업체

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