MRT-10;MRT-10 >=98% (HPLC);N-((3-Benzamidophenyl)carbamothioyl)-3,4,5-trimethoxybenzamide;N-({[3-(benzoylamino)phenyl]amino}carbonothioyl)-3,4,5-trimethoxybenzamide;Benzamide, N-[[[3-(benzoylamino)phenyl]amino]thioxomethyl]-3,4,5-trimethoxy-;N-[[[3-[(Benzoyl)amino]phenyl]amino](thioxo)methyl]-3,4,5-trimethoxybenzamide;ShhN signaling,inhibit,MRT10,MRT 10,cancer,Smoothened,Smo,Smo-induced IP accumulation,MRT-10,Bodipy-cyclopamine,SAG-induced AP activity,Inhibitor
눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P501
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NFPA 704
0
3
0
N-[[[3-[(벤조일)아미노]페닐]아미노](티옥소)메틸]-3,4,5-트리메톡시벤즈아미드 C화학적 특성, 용도, 생산
개요
MRT10 is an antagonist of the Smoothened (Smo) receptor with an IC50 value of 0.64 μM in a luciferase reporter assay. It also inhibits bodipy-cyclopamine binding to the murine Smo receptor (IC50 = 0.5 μM) when expressed in HEK293 cells.
용도
MRT 10, is a novel, high-affinity antagonist smoothened (Smo) receptor antagonist. It displaces labeled cyclopamine from Smo with an IC50 of 500 nM, and inhibits shh-induced Gli-reporter activity in Shh-light2 cells (IC50 = 0.64 μM).
N-[[[3-[(벤조일)아미노]페닐]아미노](티옥소)메틸]-3,4,5-트리메톡시벤즈아미드 준비 용품 및 원자재
원자재
준비 용품
N-[[[3-[(벤조일)아미노]페닐]아미노](티옥소)메틸]-3,4,5-트리메톡시벤즈아미드 공급 업체