카올린

카올린 속성

카올린 C화학적 특성, 용도, 생산

순도시험

  (1) 물가용물 및 액성 : 이 품목 10g에 물 100mL를 가하여 증발하는 물을 보충하면서 30분간 끓이고 식힌 다음 물을 가하여 100mL로 하고 유리여과기(3G4)로 여과할 때, 여액의 액성은 pH 6.0～8.0이어야 한다. 또 이 여액 50mL를 취하여 증발건고하고 잔류물을 105℃에서 1시간 건조할 때, 그 양은 15mg 이하이어야 한다.

  (2) 산가용물 : 이 품목 1g에 황산(1→15) 20mL를 가하여 15분간 흔들어 섞고 여과한다. 그 여액 10mL를 취하여 증발건고하고 다시 항량이 될 때까지 강열할 때, 그 잔류물은 10mg 이하이어야 한다.

  (3) 비소 : 이 품목을 비소시험법에 따라 시험할 때, 그 양은 4.0ppm 이하이어야 한다.

  (4) 납 : 이 품목 5.0g을 취하여 원자흡광광도법 또는 유도결합플라즈마발광광도법에 따라 시험할 때, 그 양은 10.0ppm 이하이어야 한다.

  (5) 이물 : 이 품목 5g에 물 300mL를 가하여 저어 섞은 다음 30초간 방치한다. 미립자를 포함한 액의 대부분을 기울여 버리고 그릇 바닥에 남은 부분을 끝이 평평한 유리봉으로 누를 때, 모래에 의한 소리가 나서는 아니 된다.

확인시험

  (1) 이 품목 0.2g을 무수탄산나트륨 및 무수탄산칼륨의 같은 양의 혼합물 0.5g과 혼합하여 백금도가니 또는 니켈도가니에 놓고 완전히 용해될 때까지 가열한다. 식힌 다음 물 5mL를 가하고 약 3분간 방치한 다음 도가니의 바닥을 약하게 가열하여 떨어진 응고물을 물과 함께 비이커에 옮기고 거품이 발생하지 아니할 때까지 염산을 조금씩 가한 다음 염산 10mL를 더 가하고 수욕상에서 증발건고한다. 이에 물 200mL를 가하여 끓인 다음 여과하고 겔상의 잔류물을 백금접시에 옮겨 불화수소산 5mL를 가하면 녹고 가열하면 거의 휘산한다.

  (2) 위 (1)의 여액은 확인시험법 중 알루미늄염의 반응을 나타낸다.

  (3) 이 품목 8g에 물 5mL를 가하여 잘 혼합한 것은 가소성으로 된다.

정의

  이 품목은 백도토에서 얻어지는 것으로서 주성분은 함수규산알루미늄이다.

개요

Kaolin or china clay is a naturally occurring, almost white, hydrated aluminum silicate. This material does not exhibit a high degree of slip. Kaolin boasts good absorbency, is dense, and is sometimes used to reduce the bulk densities in loose powder products. It provides a matte surface effect, which can slightly reduce sheen left by some talc products.

화학적 성질

Kaolin occurs as a white to grayish-white colored, unctuous powder free from gritty particles. It has a characteristic earthy or claylike taste, and when moistened with water it becomes darker in color and develops a claylike odor.

물리적 성질

Sericite is a mineral similar to white mica in shape and composition. It has a very fine grain size and a silky shine. This material is soft and smooth and has a slippery feel on the skin. Sericite may be coated with silicone and other treatments for enhanced water repellency and skin adhesion.

출처

Kaolin is a naturally occurring clay that is treated for impurities.

용도

kaolin (China clay) is a mixture of various aluminum silicates. It is often used in powders and masks given its absorbent, abrasive, bulking, and opacifying properties. This white, soft powder has good coverage and absorption abilities for both water and oil, making it an appropriate absorber of the oil and sweat secreted by the skin. It adheres well to the skin’s surface, yet is easily removed with normal cleansing procedures. Kaolin is considered a non-comedogenic raw material.

Indications

Kaolin is a naturally occurring hydrated aluminum silicate that is prepared for medicinal use as a very finely divided powder. The rationale behind its use in acute nonspecific diarrhea stems from its ability to adsorb some of the bacterial toxins that often cause the condition.

정의

A mixture of clays, quartz, and feldspar usually containing at least 25% alumina. Ball and china clays are ordinarily used. A slip or slurry is formed with water to form a plastic, moldable mass, which is then glazed and fired to a hard, smooth solid.

생산 방법

Kaolin is a hydrated aluminum silicate obtained by mining naturally occurring mineral deposits. Large deposits are found in Georgia, USA and in Cornwall, England.
Mined kaolin is powdered and freed of coarse, gritty particles either by elutriation or by screening. Impurities such as ferric oxide, calcium carbonate, and magnesium carbonate are removed with an electromagnet and by treatment with hydrochloric acid and/or sulfuric acids.

제조 방법

The extraction of KAOLIN (china clay) from its deposits is usually performed in three steps: open-pit mining, mineral processing and beneficiation, and drying.
Open-pit operations require the removal of ground overlying the clay (i.e., overburden). The exposed clay is then mined by a hydraulic mining process, that is, a high-pressure water jet from a water cannon called a monitor erodes the faces of the pit. This liberates from the quarry face the china clay, together with sand and mica. The slurry formed flows to the lowest part of the pit or sink, where it is pumped by centrifugal pumps to classifiers, where coarse silica sand is removed. The silica sand is later reused for landscape rehabilitation. The remaining suspension of clay is transported by underground pipeline to the mineral-processing and beneficiation plant, where a series of gravity separation techniques are used to remove particulate materials such as quartz, mica, and feldspars. Sometimes the purified clay slurry undergoes an additional chemical bleaching process that greatly improves its whiteness. The refined clay suspension is then filtrated, and the filtration cake with a moisture content of about 25 wt.% passes through a thermal drier fired by natural gas to yield a final product with 10 wt.% moisture. The end product is normally sold in pelletized form with a pellet size ranging from 6 to 12 mm.

World Health Organization (WHO)

Kaolin, a hydrated aluminium silicate, is an absorbent and has been used to treat diarrhoea because of its ability to bind and inactivate bacterial toxins. However, it has been shown to induce only a slight change in stool consistency and there is no evidence that it can reduce the duration or the severity of diarrhoeal disease. It does not reduce fluid and electrolyte losses. It cannot be recommended in the treatment of diarrhoea.

일반 설명

Odorless white to yellowish or grayish powder. Contains mainly the clay mineral KAOLINite (Al2O3 SiO2)2 H2O)2), a hydrous aluminosilicate. KAOLINite has mp 740-1785°C and density: 2.65 g cm-3. KAOLINe is insoluble in water but darkens and develops a earthy odor when wet.

반응 프로필

KAOLIN is stable and chemically unreactive under ordinary conditions.

위험도

Respirable fraction; questionable carcinogen.

Pharmaceutical Applications

Kaolin is a naturally occurring mineral used in oral and topical pharmaceutical formulations.
In oral medicines, kaolin has been used as a diluent in tablet and capsule formulations; it has also been used as a suspending vehicle. In topical preparations, sterilized kaolin has been used in poultices and as a dusting powder. Therapeutically, kaolin has been used in oral antidiarrheal preparations.

공업 용도

The name kaolin comes from the two Chinese words kao-ling, meaning high ridge, and was originally a local term used to describe the region from which the clay was obtained. Kaolin (Al₂O₃2SiO₂2 H₂O) usually contains less than 2% alkalies and smaller quantities of iron, lime, magnesia, and titanium. Because of its purity, kaolin has a high fusion point and is the most refractory of all clays. Lone kaolins are widely used in casting sanitaryware, ceramics, and refractories.
Georgia china clay is one of the most uniform kaolins to be found. Generally speaking, there are two types of Georgia-sourced kaolin, both of which are widely used for casting and other processes. One type imparts unusually high strength and plasticity, and is used for both casting and jiggering where a high degree of workability is required. The other type typically is a fractionated, controlled particle size clay that also behaves well in casting, dries uniformly, and reduces cracking of ware.

부작용

It is almost harmless and is effective in many cases of diarrhea if taken in large enough doses (2–10 g initially, followed by the same amount after every bowel movement). The adsorbents are generally safe, but they may interfere with the absorption of some drugs from the GI tract.

Safety

Kaolin is used in oral and topical pharmaceutical formulations and is generally regarded as an essentially nontoxic and nonirritant material. Oral doses of about 2–6 g of kaolin every 4 hours have been administered in the treatment of diarrhea.

Source

Premier-quality deposits of kaolin such as those mined in Cornwall in the United Kingdom, Georgia and the Carolinas in the southe astern United States, and the Amazon Basin of Brazil.
Other suppliers of quality kaolin include France, Germany, the Czech Republic, Malaysia, and Australia.

저장

Kaolin is a stable material. Since it is a naturally occurring material, kaolin is commonly contaminated with microorganisms such as Bacillus anthracis, Clostridium tetani, and Clostridium welchii. However, kaolin may be sterilized by heating at a temperature greater than 160°C for not less than 1 hour. When moistened with water, kaolin darkens and becomes plastic.
Kaolin should be stored in a well-closed container in a cool, dry place.

비 호환성

The adsorbent properties of kaolin may influence the absorption of other orally administered drugs. Drugs reportedly affected by kaolin include amoxicillin; ampicillin;cimetidine; digoxin; lincomycin; phenytoin; and tetracycline. Warfarin absorption by rat intestine in vitro was reported not to be affected by kaolin. With clindamycin, the rate (but not the amount) of absorption was affected by kaolin.

Regulatory Status

Accepted in Europe as a food additive in certain applications. Included in the FDA Inactive Ingredients Database (oral capsules, powders, syrups, and tablets; topical preparations). Included in nonparenteral medicines licensed in the UK.

카올린 준비 용품 및 원자재

원자재

준비 용품

카올린 공급 업체

공급자	전화	이메일	국가	제품 수	이점
ShanDong Look Chemical Co.,Ltd.	+8617653113219	sales01@sdlookchemical.com	China	2737	58
Hebei Weibang Biotechnology Co., Ltd	+8615531157085	abby@weibangbio.com	China	8810	58
Shaanxi Dideu Medichem Co. Ltd	+86-29-81148696 +86-15536356810	1022@dideu.com	China	3882	58
Hebei Mojin Biotechnology Co., Ltd	+86 13288715578 +8613288715578	sales@hbmojin.com	China	12837	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20285	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	+8618092446649	sarah@tnjone.com	China	1143	58
Yujiang Chemical (Shandong) Co.,Ltd.	+86-17736087130 +86-18633844644	catherine@yjchem.com.cn	China	990	58
Hebei Zhuanglai Chemical Trading Co.,Ltd	+8613343047651	admin@zlchemi.com	China	3002	58
Hebei Shengyang Water Conservancy Engineering Co., Ltd.	+8615373025980	clara@hbshengyang.com	China	875	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21634	55

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