FzM1
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FzM1 속성
- 끓는 점
- 518.3±50.0 °C(Predicted)
- 밀도
- 1.401±0.06 g/cm3(Predicted)
- 저장 조건
- Store at -20°C
- 용해도
- DMF: 12 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.2 mg/ml; DMSO: 10 mg/ml
- 물리적 상태
- 결정성 고체
- 산도 계수 (pKa)
- 9.42±0.10(Predicted)
- 색상
- White to light brown
FzM1 C화학적 특성, 용도, 생산
개요
Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis. Wnt proteins initiate cell signaling by binding Frizzled (Fz) receptors, a family of G protein-coupled receptors. FzM1 is an allosteric ligand of Fz4. At 10 μM, it inhibits nuclear translocation of β-catenin in U87MG glioma cells treated with lithium chloride, a GSK3 inhibitor that enhances the Wnt canonical signaling pathway. FzM1 impairs the ability of U87MG cells to form neurospheres in culture and stimulates the differentiation of Caco-2 epithelial colorectal adenocarcinoma cells.FzM1 준비 용품 및 원자재
원자재
준비 용품
FzM1 공급 업체
글로벌( 18)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 |
757984502@qq.com | China | 892 | 58 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9707 | 58 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 |
sales@rechemscience.com | China | 2966 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 |
sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
| ShangHai ChuanQian Chemcial Technique Centre | 15869524721 |
3525679403@qq.com | China | 3715 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 |
marketing1@energy-chemical.com | China | 44843 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 |
order@med-bio.cn | China | 8141 | 58 |