0 - 4℃ for short term (days to weeks), or -20℃ for long term (months).
물리적 상태
고체
물리적 상태
단단한 모양
색상
하얀색
수용성
Water : 5 mg/mL (7.88 mM)
안전
Ensartinib dihydrochloride C화학적 특성, 용도, 생산
개요
Ensartinib
HCl is the salt form of Ensartinib, an orally available small molecule
inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase
(ALK) with potential antineoplastic activity. Upon oral administration,
X-396 binds to and inhibits ALK kinase, ALK fusion proteins and ALK
point mutation variants. Inhibition of ALK leads to the disruption of
ALK-mediated signaling and eventually inhibits tumor cell growth in
ALK-expressing tumor cells. ALK belongs to the insulin receptor
superfamily and plays an important role in nervous system development.
