베르테로인
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베르테로인 속성
- 녹는점
- 155～156℃
- 끓는 점
- 155 °C(Press: 10 Torr)
- 밀도
- 1.01±0.1 g/cm3(Predicted)
- 저장 조건
- Store at -20°C
- 용해도
- DMF: 3 mg/ml; DMSO: 16 mg/ml; Ethanol: 20 mg/ml; PBS (pH 7.2): 10 mg/ml
- 냄새
- 프로필렌 글리콜 중 0.01%. 양배추 무
- ?? ??
- 무
- JECFA Number
- 1896
- LogP
- 2.67
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
베르테로인 C화학적 특성, 용도, 생산
개요
Berteroin is a sulforaphane analog found in cruciferous vegetables including Chinese cabbage, rucola salad leaves, and mustard oil. At 1.7 μM, it has been shown to double the phase II enzyme quinone reductase activity in mouse hepatoma cells. Berteroin exerts anti-inflammatory activity in LPS-stimulated RAW 264.7 macrophages, inhibiting degradation of IκBα, as well as NF-κB p65 translocation to the nucleus and DNA binding activity. It also suppresses IRAK degradation and phosphorylation of TAK1, p38 MAPK, ERK1/2, and Akt.화학적 성질
Pale yellow liquid; penetrating radish-like aroma출처
Reported found in radish and horseradish.효소 저해제
This sulforaphane analogue and antimetastatic agent (FW = 175.43 g/mol; CAS 4430-42-6; Physical State = Liquid; Soluble in ethanol, DMSO, and chloroform; Store at -20° C; M.P. = 155-156° C), also named 5- methylthiopentyl isothiocyanate, is found in cruciferous vegetables (including Chinese cabbage and rucola leaves) and mustard oil. Berteroin inhibits LPS-induced degradation of Inhibitor of κBα (or IκBα) as well as NF-κB p65 translocation into the nucleus and DNA binding. Berteroin also suppresses degradation of IL-1 Receptor Associated Kinase and phosphorylation of Transforming Growth Factor β-Activated Kinase-1. Berteroin also inhibits LPS-induced phosphorylation of p38 MAPK, ERK1/2, and AKT베르테로인 준비 용품 및 원자재
원자재
이소티오시안산4-펜텐-1-일에스테르
5-(메틸티오)-1-펜탄아민
5-(methylthio)-valeronitrile,5-(methylthio)-pentanenitrile,1-cyano-4-(methylthio)butane,5-methylthiopentanenitrile
5-BROMOVALERONITRILE
메틸메르캅탄(기체)
티오포스겐
5-브로모-1-펜텐
준비 용품
베르테로인 공급 업체
글로벌( 40)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 52927 | 58 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 |
sales@glpbio.cn | China | 6870 | 58 |
| Shanghai wencai New Material Technology Co., Ltd. | 15721586846 |
wencaimat@163.com | China | 2796 | 58 |
| BOC Sciences | -- |
info@bocsci.com | USA | 0 | 65 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 |
order@med-bio.cn | China | 8141 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 |
marketing@energy-chemical.com | China | 44941 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 |
3477467573@qq.com | China | 8618 | 58 |
| TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 24017 | 58 |