Protectin D1
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Protectin D1 속성
- 끓는 점
- 559.4±50.0 °C(Predicted)
- 밀도
- 1.048±0.06 g/cm3(Predicted)
- 저장 조건
- Store at -20°C
- 용해도
- DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.1 mg/ml
- 물리적 상태
- Liquid
- 산도 계수 (pKa)
- 4.58±0.10(Predicted)
- 색상
- Colorless to light yellow
안전
Protectin D1 C화학적 특성, 용도, 생산
개요
Protectin D1 is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid (DHA; ). DHA is oxidized to 16S,17S-epoxy-protectin, which is converted to protectin D1 enzymatically. Protectin D1 increases phagocytosis of apoptotic polymorphonuclear leukocytes (PMNs) by macrophages in a non-phlogistic manner and is generated in vitro during macrophage-apoptotic interactions. It enhances phagocytosis in mice after 24 hours, but not at the initiation or peak of inflammation. It also decreases PMN infiltration in a zymosan-induced mouse model of inflammation when administered at a dose of 300 ng per animal. Protectin D1 (200 μg, i.v.) inhibits increases in neutrophil counts in bronchoalveolar fluid (BALF) and lung myeloperoxidase activity in a mouse model of pulmonary injury and inflammation induced by intratracheal LPS instillation. It also decreases pulmonary edema and promotes neutrophil apoptosis in BALF.용도
Protectin D1 is a potent anti-inflammatory lipid mediator.Protectin D1 준비 용품 및 원자재
원자재
준비 용품
Protectin D1 공급 업체
글로벌( 7)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 |
sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
| amyjetsci | 027-59626688 18771149750 |
sales@amyjet.com | China | 3004 | 58 |
| Beijing Biocreative Technology Co., Ltd. | 15522676233 |
3007606172@qq.com | China | 1249 | 58 |
| TargetMol Chemicals Inc. | 4008200310 |
marketing@tsbiochem.com | China | 24017 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 |
customer_service@efebio.com | China | 8739 | 58 |