ANTI-HSP40
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ANTI-HSP40 속성
- 저장 조건
- −20°C
- 물리적 상태
- 완충 수용액
안전
| WGK 독일 | - |
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ANTI-HSP40 C화학적 특성, 용도, 생산
용도
Anti-Heat Shock Protein 40 antibody produced in rabbit has been used in western blotting and microarray.일반 설명
Cells express an increased amount of several highly conserved proteins referred to as heat shock or heat stress proteins (Hsps). They are primarily found in the cytoplasm, nucleus, and mitochondria. Mammalian cells Hsps are classified into several families of sequence-related proteins, which are differentiated by their molecular sizes. Major families are as follows: the Hsp25/Hsp27/Hsp28 family (the small stress proteins), the Hsp40 family, the Hsp60 family, the Hsp70 family, the Hsp90 family, and the Hsp110/SSE family. HSP40, also known as DNAJB1, HSPF1, or HDJ1, is a 339-amino acid, stress inducible heat shock protein, that is homologous to the bacterial heat shock protein DnaJ, and to the yeast DnaJ-related proteins such as SCJ1, Sec63/Np11, YDJ1, and SIS1.Biochem/physiol Actions
In heat-shocked cells, Hsp40 translocates from the cytoplasm to the nucleus and nucleoli, colocalizing with Hsp70. Hsp40 and Hsp70 have been implicated in reduction of protein aggregates produced in neurodegenerative diseases, such a Huntington′s and Parkinson′s diseases. In brain tissues from Parkinson disease patients, it has been shown that Lewy bodies (LBs) and Lewy neurites (LNs) are immunopositive for Hsp70 and Hsp40 chaperones, suggesting that altered chaperone activity may be involved in progression of Parkinson disease.ANTI-HSP40 준비 용품 및 원자재
원자재
준비 용품
ANTI-HSP40 공급 업체
글로벌( 16)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Beijing Zhijie Fangyuan Technology Co., Ltd. | -- |
15810200961@163.com | CHINA | 6984 | 58 |
| Shanghai Yijie Biological Technology Co., Ltd. | -- |
SHYIJIEBIO@126.COM | CHINA | 3510 | 58 |
| Beijing Taize Jiaye Technology Development Co., Ltd. | -- |
CHINA | 6050 | 58 | |
| Shanghai Yubo Biotechnology Co., Ltd. | -- |
shybio@126.com | CHINA | 6969 | 58 |
| Shanghai Haoran Biotechnology Co., Ltd. | -- |
470003480@QQ.COM | CHINA | 6968 | 58 |
| Shanghai Ziqi Biological Technology Co., Ltd. | -- |
2453006496@qq.com | CHINA | 6192 | 58 |
| Beijing Bi Orange Blue Biotechnology Co., Ltd. | -- |
bo49855987@163.com | CHINA | 6827 | 58 |
| BEIJING BIOSYNTHESIS BIOTECHNOLOGY CO., LTD. | -- |
sales@bioss.com.cn | CHINA | 6717 | 58 |
| Shanghai Zeye Biotechnology Co., Ltd. | -- |
shzeysw@163.com | CHINA | 6550 | 58 |
| Riedel-de Haen AG | -- |
United States | 6825 | 87 |