미안세린

미안세린
미안세린 구조식 이미지
카스 번호:
24219-97-4
한글명:
미안세린
동의어(한글):
미안세린
상품명:
MIANSERIN
동의어(영문):
Depnon;Org-4360;Org-5859;MIANSERIN;MIANSERINE;(S)-Mianserine;(R)-Mianserine;Mianserin USP/EP/BP;Mianserin Impurity 14;MIANSERIN,1.0MG/MLINMETHANOL
CBNumber:
CB6679015
분자식:
C18H20N2
포뮬러 무게:
264.36
MOL 파일:
24219-97-4.mol

미안세린 속성

끓는 점
397.6°C (rough estimate)
밀도
1.0092 (rough estimate)
굴절률
1.5200 (estimate)
저장 조건
Store at -20°C
용해도
DMSO에 용해됨
물리적 상태
가루
산도 계수 (pKa)
pKa 7.5(H2O,t =20.0) (Uncertain)

안전

유엔번호(UN No.) 3249
위험 등급 6.1(b)
포장분류 III
유해 물질 데이터 24219-97-4(Hazardous Substances Data)

미안세린 C화학적 특성, 용도, 생산

용도

Serotonin receptor antagonist. Antidepressant

World Health Organization (WHO)

Mianserin, a serotonin antagonist with antidepressant and antihistaminic activity, was introduced in 1975 for the treatment of depressive illness. Its use has since been associated with cases of severe blood dyscrasias, particularly in elderly patients, including agranulocytosis, leucopenia and granulocytopenia. Several drug regulatory authorities have reacted by stipulating that blood counts should be monitored regularly during the first few months of treatment and that administration should be discontinued immediately should any signs possibly indicative of dyscrasia develop.

미안세린 준비 용품 및 원자재

원자재

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